HEART HEALTH COLLECTION

Protect the engine
that drives everything.

Cardiovascular health is the single most consequential system in the body. Every product here has been evaluated for clinical evidence, purity, and bioavailability — nothing makes it in on marketing alone.*
Practitioner-Curated Formulas
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HEART HEALTH 101

The system that drives everything else.

Cardiovascular health is the most consequential system in the body — and the most misunderstood. Here's a clear primer on the four pillars of heart support, why nutrient form matters more than dose, and how we choose what earns its place here at Pure Prescriptions.
01

Why Heart Health Matters

Cardiovascular wellness is one of the most consequential investments you can make in long-term health — and it develops silently for decades before signs appear. Blood pressure, cholesterol, inflammation, and endothelial function are not isolated numbers; they are interconnected systems. Supporting them early, with the right nutrients, is the single most consequential investment you can make in long-term health.*

02

The Four Pillars

A complete heart protocol addresses four areas: circulation (nattokinase, omega-3), cellular energy (CoQ10), lipid balance (red yeast rice, berberine), and vascular integrity (NAC, magnesium). No single supplement covers all four — each plays a distinct, evidence-supported role in the cardiovascular picture.

  • Circulation · Nattokinase, Omega-3
  • Cellular Energy · CoQ10
  • Lipid Balance · RYR, Berberine
  • Vascular Integrity · NAC, Magnesium
03

Form & Bioavailability

The form a nutrient takes matters as much as the dose. Ubiquinol — not ubiquinone — is the active, reduced form of CoQ10 your heart actually uses. Cardiokinase® is the clinically recognized nattokinase enzyme with measurable fibrinolytic activity. Triglyceride-form omega-3 absorbs far better than the cheaper ethyl-ester alternative. We carry the forms the research was actually run on.

Heart Collection

The Practitioner's Protocol

For over 25 years, Dr. Devin Ryerson — founder of Pure Prescriptions — has personally evaluated thousands of formulas across every tier of the supplement industry. What you find here are the products that earned their place on merit alone. Each category leads with a single best-first recommendation, then ranks the additions that build on it.

Browse By

Heart Health

466 practitioner-curated products - organized by clinical priority.

Health Goal

Blood Pressure & Circulation

Support healthy vascular tone, blood flow, and arterial flexibility.

Cardiokinase®

$65.00

What It Does For You
  • Supports healthy blood pressure & circulation*
  • Promotes fibrinolytic activity for blood flow*
  • HTNK-J® — highest-purity nattokinase*
  • Endorsed by its discoverer*
Format
Soft Gels
Dose
2 daily
When
With a meal

Also ConsiderIn Order of Priority

Ranked by clinical impact. Start with 02 and add one product at a time — each one builds on what came before, so your results grow stronger the longer you stay consistent.

Metagenics ArginCor(R) -- endothelial function support, wound care.
Blood Pressure & Circulation

ArginCor®

Clinical-dose arginine for endothelial function and nitric oxide synthesis.

$74.95

Health Goal

Cholesterol & Lipids

Manage LDL, triglycerides, and lipid oxidation at the source.

Premium Omega-3 Plus

$49.97

What It Does For You
  • Lowers triglycerides, raises HDL*
  • Reduces arterial inflammation from oxidized LDL*
  • VESIsorb® — 300% better absorption*
  • Includes D3 + K2 for arterial calcium*
Format
Soft Gels
Dose
2 daily
When
With a meal

Also ConsiderIn Order of Priority

Ranked by clinical impact. Start with 02 and add one product at a time — each one builds on what came before, so your results grow stronger the longer you stay consistent.

Cholesterol & Lipids

Red Yeast Rice

Naturally contains monacolin K — the same active compound as prescription lovastatin — for direct LDL reduction without the side effects of synthetic statins.

$44.95

Metagenics Berberine GT -- heart health, weight management.
Cholesterol & Lipids

Berberine GT

Activates AMPK — the same pathway as statins but via a natural mechanism, with 50+ clinical trials.

$44.95

Health Goal

Mitochondria & Cardiac Energy

The heart muscle demands more energy than any other organ in the body.

Bioactive CoEnzyme Q10

$59.97

What It Does For You
  • Ubiquinol — the active form your body uses*
  • Direct fuel for cardiac mitochondria*
  • Non-negotiable if taking statins*
  • Energy for every cell in your body*
Format
Soft Gels
Dose
1–2 daily
When
With a fat-containing meal

Also ConsiderIn Order of Priority

Ranked by clinical impact. Start with 02 and add one product at a time — each one builds on what came before, so your results grow stronger the longer you stay consistent.

NMN - Healthy Aging Support by InfiniWell
Mitochondria & Cardiac Energy

NMN – Healthy Aging Support

NMN is a direct NAD+ precursor — the heart muscle demands more NAD+ than any other tissue to sustain mitochondrial output. Enhanced with trans-resveratrol and pterostilbene for synergistic anti-aging support.

$69.99

Perfect Creatine Front Of Canister
Mitochondria & Cardiac Energy

Perfect Creatine™

Creatine directly fuels ATP resynthesis in heart muscle — the heart's phosphocreatine pool is its emergency energy reserve during ischemic stress.

$29.97

DaVinci Labs NAD+ Activate with Glutathione -- healthy aging, cellular energy.
Mitochondria & Cardiac Energy

NAD+ Activate with Glutathione

Pairs Bioenergy RiaGev-WS® (ribose + nicotinamide ascorbate) with Provail® glutathione — fueling NAD+ synthesis and protecting cardiac mitochondria from oxidative damage simultaneously.

$54.98

Health Goal

Inflammation & Oxidative Stress

Chronic inflammation is the root driver of vascular and arterial wear.*

Curcumin C3 Complex

$46.00

What It Does For You
  • Inhibits NF-κB — master inflammation switch*
  • Reduces CRP & inflammatory cytokines*
  • Protects arterial lining from oxidation*
  • C3 Complex® — most clinically researched*
Format
Capsules
Dose
1–2 daily
When
With a fat-containing meal

Also ConsiderIn Order of Priority

Ranked by clinical impact. Start with 02 and add one product at a time — each one builds on what came before, so your results grow stronger the longer you stay consistent.

Health Goal

Methylation & Structural Support

Homocysteine, B-vitamins, and D3+K2 form the overlooked foundation of heart longevity.

Activated B-Complex

$26.00

What It Does For You
  • Lowers homocysteine — a heart risk factor*
  • Quatrefolic® — bypasses MTHFR mutations*
  • Supports methylation for heart & brain*
  • Activated forms — no conversion needed*
Format
Capsules
Dose
1–2 daily
When
With a meal

HEART HEALTH · FULL CATALOG

Still Not Finding What You're Looking For?

Browse the complete Heart Health catalog — every product, every brand, sorted A–Z for easy discovery.SHOP ALL HEART HEALTH