THE ENZYME COLLECTION

The catalysts behind
every reaction.

Enzymes are biological catalysts — they make the chemical reactions that sustain life happen fast enough to matter. Digestive enzymes break down food. Systemic enzymes like nattokinase and serrapeptase support circulation and a healthy inflammatory response. Without them, nothing works efficiently.*
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ENZYMES 101

What enzymes are, and why they matter.

Enzymes are one of the most underappreciated categories in supplementation. They don't nourish like vitamins or minerals — they catalyze. Here's what digestive and systemic enzymes actually do, and when to use them.*
01

What Are Enzymes?

Enzymes are proteins that speed up chemical reactions without being consumed. Your body makes thousands of them — for digestion, detoxification, tissue repair, and energy production. Each enzyme is specific: protease breaks protein, lipase breaks fat, amylase breaks carbohydrate.

02

Digestive vs. Systemic

Digestive enzymes (taken with food) break down what you eat, reducing bloating and improving nutrient absorption. Systemic enzymes (taken between meals) enter circulation and work throughout the body — supporting healthy inflammation, circulation, and tissue repair.

  • PROTEASE · PROTEIN BREAKDOWN
  • LIPASE · FAT DIGESTION
  • NATTOKINASE · CIRCULATION
  • SERRAPEPTASE · INFLAMMATION
03

Why Supplement?

Natural enzyme production declines with age. Cooked and processed foods have none. If you experience bloating, gas, or sluggish digestion after meals — or want circulatory support — enzyme supplementation can make a noticeable difference within days.

04

What to Look For

Broad-spectrum blends (not just a single enzyme), activity units listed (not just mg weight), and enteric coating for systemic enzymes. Every product comes with a Certificate of Analysis (COA) for verified potency. That's the only kind we carry.

ENZYMES COLLECTION

The Practitioner's Protocol

For over 25 years, Dr. Devin Ryerson â€” founder of Pure Prescriptions — has personally evaluated thousands of formulas. What you find here are the products that earned their place on merit alone. Each category leads with a single best-first recommendation, then ranks the additions that build on it.

Browse By

Enzymes

67 practitioner-curated products - organized by clinical priority.

Health Goal

Digestive Enzymes

Broad-spectrum enzymes taken with food to break down proteins, fats, and carbohydrates — for comfortable, complete digestion.

Digestive Enzymes

$29.97

What It Does For You
  • Broad-spectrum blend — protease, lipase, amylase, cellulase, and lactase*
  • Breaks down difficult-to-digest foods like dairy, beans, and cruciferous vegetables*
  • Reduces post-meal bloating, gas, and sluggishness*
  • Plant-derived enzymes active across the full digestive tract*
Format
Capsules
Dose
1–2 capsules with meals
When
Before or during meals
More InfoAdd to cart

BONUS PICK

ADD ONLY IF NEEDED A targeted add-on — not part of the core stack. Add only if it matches your specific needs.

Health Goal

Circulation & Cardiovascular

Systemic nattokinase enzymes taken between meals to support fibrin balance, blood flow, and heart health.

Cardiokinase®

$65.00

What It Does For You
  • The only nattokinase endorsed by Dr. Hiroyuki Sumi — its original discoverer*
  • HTNK-J® strain — the most potent nattokinase available, 2,500 FU per softgel*
  • Nutrition Business Journal Product Merit Award winner*
  • Supports healthy fibrin balance, blood flow, and cardiovascular function*
Format
Softgels
Dose
1–3 softgels daily
When
With food; one dose before bed
More InfoAdd to cart

Also ConsiderIn Order of Priority

Ranked by clinical impact. Start with 02 and add one product at a time — each one builds on what came before, so your results grow stronger the longer you stay consistent.

Circulation & Cardiovascular

Nattokinase NSK-SD®

The original clinically studied nattokinase extract — patented NSK-SD® delivering 2,000 FU per capsule and all vitamin K removed. An alternative format, not an addition: same goal, different strain. Most users choose one or the other based on potency preference and budget.

Original price was: $98.00.Current price is: $89.00.

More InfoAdd to cart

Health Goal

Proteolytic & Inflammatory Balance

Systemic protein-digesting enzymes for healthy inflammatory response, respiratory, and tissue support.

Serrapeptase 60,000 Units

$25.00

What It Does For You
  • Powerful protein-digesting enzyme derived from Serratia marcescens*
  • Supports a healthy inflammatory response throughout the body*
  • Helps maintain normal mucus secretions for respiratory health*
  • Absorbed intact from the gut for whole-body (systemic) activity*
Format
Veg Capsules
Dose
1 capsule daily
When
Empty stomach with water
More InfoAdd to cart

BONUS PICK

ADD ONLY IF NEEDED A targeted add-on — not part of the core stack. Add only if it matches your specific needs.

Health Goal

Food-Specific Intolerances

Targeted enzymes for gluten, dairy, FODMAPs, and other specific food triggers general blends miss.

Full Spectrum Digest with Glutalytic

$63.79

What It Does For You
  • Comprehensive vegan enzyme blend with Glutalytic® for gluten and casein*
  • Includes DPP-IV — the enzyme specifically responsible for digesting gluten*
  • Lactase for dairy, alpha-galactosidase for beans and cruciferous vegetables*
  • Protease, amylase, and lipase for broad-spectrum macronutrient digestion*
Format
Vegan Capsules
Dose
1 capsule with meals
When
1–3 times daily with food
More InfoAdd to cart

BONUS PICK

ADD ONLY IF NEEDED A targeted add-on — not part of the core stack. Add only if it matches your specific needs.

ENZYMES · FULL CATALOG

Still Not Finding What You're Looking For?

Browse the complete Enzyme catalog — every digestive, systemic, and specialty enzyme formula we carry, sorted A–Z.SHOP ALL ENZYME PRODUCTS

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Three ways to
discover what's right for you.

The supplement world is noisy. We've built three distinct paths — so wherever you're starting from, we can guide you to exactly what your body needs.
For the uncertainWellness QuizAnswer a few questions about your health goals and receive a practitioner-matched protocol in minutes. The fastest path from confusion to clarity.
  • 2-minute assessment
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  • Matched to your life stage
Take the QuizBy Dr. Devin RyersonThe MethodSeven hand-picked stacks developed by our founder — each targeting a specific health outcome with clinical precision. No guesswork, no compromise.
  • 7 practitioner protocols
  • Condition-specific stacks
  • Trusted since 1999
Explore The MethodFor the self-directedBundle & SaveYou know what you need. Pick from our full catalog, stack your go-to formulas, and save more as you add — up to 20% off plus a free product at 5 items.
  • 10–20% off bundles
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