THE WEIGHT MANAGEMENT COLLECTION

Science,
Not Shortcuts.

Evidence-based metabolic support — insulin sensitivity, thermogenesis, satiety signaling, and body composition — without stimulants or gimmicks.*
METABOLIC HORMONE SUPPORT
NO STIMULANTS · NO SHORTCUTS
PRACTITIONER SELECTED SINCE 1999

WEIGHT MANAGEMENT 101

How healthy weight loss actually works.

Lasting weight loss isn't about stimulants or willpower — it's about supporting the biology that regulates metabolism, appetite, and body composition. Here's what the evidence actually supports.*
01

It's Biology, Not Willpower

Metabolism, hunger, and fat storage are governed by hormones and enzymes — insulin, AMPK, leptin, ghrelin. Supplements don't replace diet and training, but the right ones support the machinery that makes your effort pay off.*

02

The Three Levers

Thermogenesis and metabolic rate (berberine), appetite and satiety signaling (fiber, chromium), and lean-mass preservation (creatine, protein). Address the lever that's holding you back rather than stacking stimulants.*

  • METABOLISM · BERBERINE
  • SATIETY · FIBER + CHROMIUM
  • LEAN MASS · CREATINE + PROTEIN
03

Preserve Muscle to Keep It Off

The people who keep weight off keep their muscle. Lean tissue burns more calories at rest and drives the strength that sustains a deficit. Creatine and adequate protein protect the tissue that makes fat loss last.*

Weight Management Collection

The Practitioner's Protocol

For over 25 years, Dr. Devin Ryerson — founder of Pure Prescriptions — has personally evaluated thousands of formulas. What you find here are the products that earned their place on merit alone. Each category leads with a single best-first recommendation, then ranks the additions that build on it.

Browse By

Weight Loss

141 practitioner-curated products - organized by clinical priority.

Health Goal

Metabolism & Thermogenesis

Evidence-based nutrients that support healthy metabolic rate and fat oxidation.

Berberine UltraSorb

$51.50

What It Does For You
  • Berbevis® phytosome — 4x more bioavailable*
  • Activates AMPK — the metabolic master switch*
  • Supports healthy insulin function and glucose*
  • Maintains healthy cholesterol and triglycerides*
Format
Capsules
Dose
1–2x daily
When
With or between meals

Also ConsiderIn Order of Priority

Ranked by clinical impact. Start with 02 and add one product at a time — each one builds on what came before, so your results grow stronger the longer you stay consistent.

Metabolism & Thermogenesis

Active B-Complex

Activated B vitamins with methylcobalamin (B12) — the cofactors that convert food into steady cellular energy.*

$26.00

Chromium Picolinate Essential mineral that supports healthy blood sugar levels and helps lessen carbohydrate cravings
Metabolism & Thermogenesis

Chromium Picolinate 500mcg

Promotes normal insulin sensitivity and helps maintain already-healthy blood sugar — reducing the carbohydrate cravings that derail consistent fat loss.*

$20.00

Health Goal

Appetite & Satiety Support

Regulate hunger hormones and support fullness signaling between meals.

PureLean® Fiber

$53.00

What It Does For You
  • 6g fiber per serving for full-spectrum satiety*
  • Glucomannan expands to promote prolonged fullness*
  • Slows digestion for healthy glycemic control*
  • Prebiotic fibers feed beneficial microflora*
Format
Powder
Dose
1–4 servings daily
When
With water

Health Goal

Body Composition & Muscle Preservation

Maintain lean muscle while losing fat — the key to a lasting metabolic shift.

Perfect Creatine Monohydrate

$36.00

What It Does For You
  • Preserves lean muscle during a caloric deficit*
  • Increases muscle cell hydration and workout output*
  • Lean muscle burns 3x more calories at rest*
  • Supports high-intensity training and EPOC*
Format
Powder
Dose
5g daily
When
Post-workout or anytime

Also ConsiderIn Order of Priority

Ranked by clinical impact. Start with 02 and add one product at a time — each one builds on what came before, so your results grow stronger the longer you stay consistent.

Thorne Whey Protein Isolate (31.9 oz Chocolate) - NSF Certified protein powder for muscle growth and recovery.
Body Composition & Muscle Preservation

Whey Protein Isolate, Chocolate

21g of highly bioavailable whey isolate per serving — rich in leucine and BCAAs that trigger muscle protein synthesis to preserve lean mass in a caloric deficit. NSF Certified for Sport with added digestive enzymes for smooth absorption.*

$65.00

Body Composition & Muscle Preservation

Klean Essential Aminos +HMB

Leucine-rich essential amino acids plus HMB — HMB reduces muscle breakdown while leucine drives synthesis, together preserving lean mass in a deficit. Added vitamin D3 supports muscle function.*

$78.00

Body Composition & Muscle Preservation

L-Glutamine Powder

L-glutamine is the most abundant amino acid in the body — it supports muscle recovery and glycogen replenishment after training, and helps preserve lean tissue during periods of caloric deficit or intense training.*

$55.00

WEIGHT MANAGEMENT · FULL CATALOG

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Browse the complete Weight Management catalog — every product, every brand, sorted A–Z for easy discovery.SHOP ALL WEIGHT MANAGEMENT