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THE HORMONE BALANCE COLLECTION
HORMONE BALANCE 101
Hormones are chemical messengers produced by endocrine glands — thyroid, adrenals, ovaries, testes, pancreas. They travel through the blood to target cells, regulating everything from energy and mood to metabolism and reproduction. Even small imbalances can cause significant symptoms.
Estrogen isn't one molecule — it's a family. The body metabolizes estrogen into "good" and "bad" pathways. DIM (diindolylmethane) and indole-3-carbinol, from cruciferous vegetables, shift metabolism toward the protective pathway. Calcium D-glucarate helps the liver clear used estrogen efficiently.
Your adrenal glands produce cortisol — the stress hormone. Chronic stress drives cortisol high, then eventually low, disrupting sleep, mood, and energy. Adaptogens like ashwagandha help regulate cortisol, while B-vitamins and vitamin C fuel adrenal hormone production. During perimenopause and beyond, shifting hormones and rising stress also raise cellular energy demands — creatine replenishes ATP, the energy currency of every cell, supporting muscle, cognitive clarity, and resilience through the transition.*
Hormone Balance Collection
Over 25 years, Dr. Devin Ryerson — founder of Pure Prescriptions — has personally evaluated thousands of formulas. What you find here are the products that earned their place on merit alone. Each category leads with a single best-first recommendation, then ranks the additions that build on it.
Browse By
HORMONES & CYCLE
Your Protocol Awaits
Your body is building its hormonal baseline. The focus here is cycle regularity, clearing excess estrogen, and laying the nutritional groundwork for decades of resilience. No hot-flash herbs — just the essentials that keep the system in rhythm.
$29.97
Ranked by clinical impact. Start with 02 and add one product at a time — each one builds on what came before, so your results grow stronger the longer you stay consistent.
Eases PMS cramps, supports progesterone production, and quiets the anxiety that spikes during the luteal phase.
$32.00
The primary intervention for PCOS and estrogen dominance — supports liver clearance of excess estrogen.
$36.00
EPA+DHA reduces the prostaglandin-driven inflammation behind painful periods and mood swings — the foundational anti-inflammatory no multivitamin can provide.
$49.97
These are the years that set the tone for what comes next — not the transition itself, but the runway before it. Stress demands peak, inflammation becomes the silent driver, and the body's hormonal reserves start to be tested. The protocol here is about holding the line: resilience, mood stability, and systemic calm so you enter the transition from a position of strength.
$29.97
Ranked by clinical impact. Start with 02 and add one product at a time — each one builds on what came before, so your results grow stronger the longer you stay consistent.
Supports the progesterone side of the equation and deepens the sleep that cortisol steals during this decade.
$32.00
Gaia PRO adaptogen blend (Rhodiola + Holy Basil) for daytime cortisol control — critical as progesterone softens and stress demands peak.
$35.50
EPA+DHA reduces the prostaglandin-driven inflammation behind painful periods and mood swings — and smooths the inflammatory load of this decade.
$49.97
Post-transition, the priorities shift to mitigation: protecting bone density, cardiovascular health, and the vasomotor symptoms that can dominate this window. The protocol becomes about sustaining the engine — keeping mitochondria, heart, and bones resilient for the long game.
$79.50
Ranked by clinical impact. Start with 02 and add one product at a time — each one builds on what came before, so your results grow stronger the longer you stay consistent.
Magnesium activates the enzymes that build bone matrix — without it, calcium cannot be properly utilized. Also quiets the sleep disruption of this phase.
$32.00
The most clinically validated herb for perimenopausal and post-menopausal hot flashes and sleep disruption.
$37.95
When estrogen's cardioprotective effect declines after menopause, omega-3s become foundational — EPA+DHA supports cardiovascular health, cognitive clarity, and the mood stability this phase depends on.
$49.97
HORMONE BALANCE · FULL CATALOG
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