THE PROMISE
The miracle mineral. The right form.
Magnesium Glycinate delivers 120mg of elemental magnesium per capsule in the highest-bioavailability form available — chelated to glycine for gentle, effective absorption. No laxative effect. Practitioner-formulated and made in the USA.
Deep, Restorative Sleep
Activates GABA receptors and regulates melatonin — helping your nervous system fully downregulate for the restorative sleep your body depends on.*
Stress & Tension Relief
Magnesium suppresses cortisol release and calms sympathetic nervous system activation — directly counteracting the physiological stress response.*
Muscle Recovery
Calcium triggers contraction; magnesium triggers release. Reduces cramping, muscle soreness, and the nighttime restlessness that disrupts recovery.*
Chelated & Absorbed
Bound to glycine for superior bioavailability. No laxative effect, no GI distress — just clean, effective magnesium your body actually uses.*
WHY IT WORKS
Whole Body Foundation
Deep, Restorative Sleep
Magnesium activates GABA receptors and regulates melatonin production. Within 1–2 weeks, most customers report falling asleep faster and waking more restored.*
Stress & Cortisol Control
Chronic stress depletes magnesium rapidly. Magnesium glycinate replenishes this reserve, directly suppressing cortisol release and calming the sympathetic nervous system activation that creates the cycle of tension and poor sleep.*
Muscle Recovery & Relaxation
Calcium triggers muscle contraction; magnesium enables the release. Without adequate magnesium, muscles stay in a state of partial contraction — leading to cramping, soreness, and nighttime restlessness. Glycinate resolves this without GI side effects.*
Cardiovascular & Metabolic Health
Adequate magnesium supports healthy blood pressure by relaxing blood vessel walls, and is associated with improved insulin sensitivity and reduced inflammatory markers. These benefits accumulate over 4–8 weeks of consistent use.*
Customer Reviews
Tried, tested,
truly loved.
Your Method
Make it your method,
not just a habit
The difference between a supplement and a method is intention. Magnesium Glycinate is designed to fit seamlessly into your evening wind-down — and work harder because of it.
Evening
Take 1–2 capsules with a full glass of water 30–60 minutes before bed. The glycinate form absorbs efficiently and begins activating your parasympathetic nervous system — preparing your body for genuinely restorative sleep.*
Why It Works
GABA receptor activation begins within 20–30 minutes. Most people notice deeper sleep within 1–2 weeks of daily use.*
Starting Out
If you’re new to magnesium supplementation, begin with one capsule daily with meals. You may gradually increase to up to four capsules per day as needed. The glycinate form is exceptionally gentle on the GI tract, making this adjustment seamless.*
Why It Works
Magnesium works cumulatively. The full effect builds over 2–4 weeks. Do not evaluate results after just a few days.
Long-Term
Magnesium is not a short-term supplement — it’s a foundational daily mineral. Missing a day occasionally won’t undo progress, but consistency over months is where the cardiovascular, metabolic, and sleep benefits fully compound.*
Why It Works
At 4–6 weeks, most customers notice significant sleep improvement. Muscle relaxation and overall wellness benefits become more noticeable at 8–12 weeks.*
How to Take It
Simple by design. Effective by science.
One to four capsules daily with meals. That's the entire protocol — no stacking, no timing complexity.
What's Inside
What's inside,
and why it matters.
The calm mineral. Delivered right.
Magnesium chelated to glycine — an amino acid with its own calming neurological properties. Among the highest bioavailability of any magnesium form, and exceptionally gentle on the GI tract.*
Chelated to glycine for superior absorption · 120 mg elemental per capsule · No laxative effect.
The amino acid of rest.
The amino acid that magnesium is chelated to in this formula. Glycine independently promotes relaxation, reduces core body temperature for sleep onset, and has shown benefits for memory consolidation.*
Amino acid chelation partner · Independently promotes relaxation and sleep onset.
Clean delivery. No gelatin.
Hydroxypropyl methylcellulose — a plant-derived capsule shell with no gelatin, no animal products, and no artificial coatings. Dissolves cleanly and consistently for predictable absorption timing.*
Plant-derived HPMC capsule · Vegan · Dissolves cleanly for predictable absorption.
Dr. Devin Ryerson
Founder & Chief Curator · Est. 1999Why It Matters
Built by someone with
personal stakes in it.
Devin started Pure Prescriptions in 1999 after battling Hodgkin's Lymphoma and losing his father to leukemia. That experience made him the most stubborn kind of formulator — one who refuses to ship anything he wouldn't take himself.
Every ingredient here earned its place through clinical evidence, third-party testing, and that same personal lens — the five collagen types, the organic fruiting-body mushrooms, the co-factors. Nothing is decorative.
"Pure Prescriptions has always been more personal than corporate. Built by family. Still independent."
Our StoryYour Journey
What to expect
Magnesium works cumulatively. Here’s what consistent daily use looks like over time.*
Week 1–2
Sleep & Calm
GABA receptor activation begins. Most people notice improved sleep quality and reduced nighttime waking within the first 1–2 weeks of consistent use.*
Magnesium Glycinate
Week 2–4
Muscle Recovery
Muscle tension and post-exercise soreness decrease as magnesium levels normalize. Recovery between training sessions improves.*
Muscle Relaxation
Week 4–8
Stress Resilience
With consistent daily use, the nervous system begins to recalibrate. Stress responses become more proportionate. Energy is more consistent throughout the day.*
Nervous System Support
Week 8–12
Cardiovascular & Metabolic
Supports cardiovascular wellness and healthy metabolic function. The long-term foundation of magnesium adequacy becomes evident.*
Full Spectrum Benefit
Results are best with daily use · Most customers see full benefits by week 8–12
Results vary from person to person.
Where Science Meets Ritual
The foundation
everything else
sits on.
“I’ve never built a protocol that didn’t start here. Not with adaptogens. Not with peptides. Magnesium first — because your mitochondria can’t produce ATP efficiently without it, your muscles can’t fully relax without it, and your nervous system can’t downregulate the way it needs to for deep sleep without it.”
- 120mg elemental magnesium per capsule
- Chelated to glycine for superior absorption
- No laxative effect — gentle on the GI tract
- Vegan · Non-GMO · Gluten-Free · Made in USA
The Evening Method
Have Questions?
Everything you need to know.
Honest answers — no marketing spin. If your question isn’t here, our team responds within one business day.
Magnesium glycinate is bound to the amino acid glycine — which has its own calming neurological properties. It has among the highest bioavailability of any magnesium form, is gentle on the GI tract, and does not cause the laxative effect associated with oxide or citrate forms. Magnesium oxide — the cheapest and most common form — has only about 4% bioavailability. Glycinate absorbs. Oxide passes through.
As a dietary supplement, take 1 capsule, up to 4 times per day, with meals. Start with one capsule for the first week to allow your body to adjust.
Most people notice improved sleep quality within 1–2 weeks of consistent daily use. Muscle relaxation and cramp reduction often appear within the first week. Cardiovascular and metabolic benefits — such as improved blood pressure and insulin sensitivity — build over 4–8 weeks and are less immediately noticeable.
Yes. Magnesium glycinate is one of the safest long-term supplements available. It is a mineral that your body requires daily — supplementation simply ensures you are meeting that requirement, particularly if your diet, stress levels, or exercise volume are working against you. There is no known toxicity concern at the label’s suggested use in healthy adults.
Yes. Magnesium works synergistically with many other compounds — particularly Vitamin D3 (required for magnesium metabolism), zinc, and CoQ10. It is compatible with the vast majority of supplement protocols. If you are taking prescription medications — particularly blood pressure medications or antibiotics — consult your practitioner.
Yes. Every batch is manufactured in an FDA-registered, GMP-certified facility in the USA and is tested for purity, potency, and the absence of contaminants. Our Certificate of Analysis is available on request.
Doctor’s Protocol
How I’d build your
recovery foundation.
“Magnesium is where I start almost every protocol. It’s the most common deficiency I see — and the one with the broadest downstream effects. Sleep, stress, muscle recovery, cardiovascular function — they all depend on it.”
In Order of Priority
4 Products · 1 Protocol
Sleep · Stress · Recovery · ATP Cofactor
Magnesium Glycinate
Start here. 120mg of elemental magnesium per capsule — the highest-bioavailability form — is the most broadly useful mineral deficiency to correct. Over 600 enzymatic reactions depend on it.
Mitochondrial Energy
Bioactive Coenzyme Q10
Magnesium is an essential cofactor in ATP synthesis — without it, the mitochondrial energy pathway CoQ10 powers is fundamentally incomplete.
Cardiovascular & Brain
Premium Omega-3 Plus
Anti-inflammatory omega-3s complement magnesium's cardiovascular benefits through complementary mechanisms — vasodilation, endothelial function, and inflammation reduction.
Skin · Joints · Recovery
Perfect Collagen + Mushroom Blend
Collagen synthesis and joint repair work best with adequate magnesium — it activates the enzymes that cross-link collagen fibers.
Add the full protocol — earn $25 store credit on your next order.
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Orders Shipped
Years in Business
Founded
Owned & Operated
In the USA
