THE PROMISE
The active form. Superior absorption. Bioactive CoQ10.
100 mg of ubiquinol delivered via VESIsorb® patented technology — a highly bioavailable CoQ10 formulation. Practitioner-recommended for cardiovascular health, mitochondrial support, and anyone over 35 or on statin therapy.*
Ubiquinol — Active Form
Unlike ubiquinone, ubiquinol is the reduced, bioavailable form your cells use directly. No conversion required — especially critical after age 35 when conversion efficiency declines.*
6× Better Absorption
VESIsorb® self-emulsifying technology converts CoQ10 into nano-sized colloidal particles in the GI tract — delivering up to 6 times the blood levels of standard softgels at the same dose.*
Heart & Brain Energy
CoQ10 is essential for ATP production — most critical in high-demand tissues: heart muscle, brain neurons, and skeletal muscle. Foundational for cardiovascular and cognitive health.*
Statin Support
Statin medications deplete CoQ10 as a direct side effect. Replenishment is strongly recommended by integrative and functional medicine practitioners for anyone on long-term statin therapy.*
WHY IT WORKS
Cellular Energy, Fully Unlocked
Cellular Energy Production
CoQ10 is essential for generating ATP — the energy currency of every cell. Most critical for high-demand tissues: heart muscle, brain neurons, and skeletal muscle.*
Cardiovascular Support
Maintains a healthy oxidative state of LDL and supports blood pressure already within the normal range — particularly important for those on statin medications, which deplete CoQ10 as a known side effect.*
VESIsorb® Delivery
Self-emulsifying technology creates a colloidal dispersion in the GI tract — proven to increase CoQ10 blood levels up to 6× vs. standard softgels at the same dose.*
Antioxidant Defense
Neutralizes free radicals across cell membranes — protecting cardiovascular tissue, brain cells, and skin from oxidative damage and age-related mitochondrial decline.*
Customer Reviews
Tried, tested,
truly loved.
Your Method
Make it your method,
not just a habit
One softgel with breakfast. That's it. CoQ10 is designed to work quietly in the background — supporting your mitochondria and cardiovascular health every single day.*
MORNING
Take one softgel with your morning meal. CoQ10 is fat-soluble — absorption is significantly higher alongside dietary fat. Morning dosing aligns its energizing effects with your peak-demand hours.*
WHY IT WORKS
VESIsorb® self-emulsifies on contact with GI fluid, forming nano-sized colloidal particles for dramatically enhanced uptake regardless of meal fat content.*
STATIN USERS
Statin medications deplete CoQ10 as a known mechanism of action. If you are on long-term statin therapy, daily CoQ10 supplementation is strongly recommended by integrative and functional medicine practitioners.*
WHY IT WORKS
Statins inhibit the mevalonate pathway, which produces both cholesterol and CoQ10. Replenishing CoQ10 supports mitochondrial function and healthy cellular energy production.*
DAILY
CoQ10 works cumulatively — plasma levels build over weeks of consistent use. Daily supplementation maintains the tissue concentrations needed for sustained cardiovascular and mitochondrial benefit.*
WHY IT WORKS
Plasma ubiquinol levels stabilize within 2–4 weeks of daily supplementation. Cardiovascular and cognitive benefits compound over months of consistent use.*
HOW TO TAKE IT
Simple by design. Effective by science.
One softgel with your morning meal. VESIsorb® technology handles the rest.
What's Inside
What's inside,
and why it matters.
What your mitochondria actually use.
The active, reduced form of CoQ10 — the precise form your mitochondria use directly. Unlike ubiquinone, ubiquinol requires no conversion, making it significantly more bioavailable, especially after age 35.
Kaneka QH® · Japan · Non-GMO · The only commercially available ubiquinol produced via natural yeast fermentation.
Kaneka QH® · Japan
6× greater absorption. Proven in clinical trials.
A patented self-emulsifying colloidal system — medium-chain triglycerides, polysorbate, and polyglycerol esters — that converts CoQ10 into nano-sized particles on contact with GI fluid. The MCT lipid base keeps CoQ10 in solution while the emulsifiers form the colloidal dispersion, delivering up to 6× greater blood levels vs. standard softgels.
Swiss Technology · EU · Clinically validated · MCT lipid base · Self-emulsifying delivery system (SEDS).
Swiss Technology · EU
Soy-free phospholipid for clean delivery.
A clean, soy-free phospholipid that supports the VESIsorb® emulsification process and aids in fat-soluble nutrient transport across the intestinal wall.
Non-GMO · Europe · Soy-free · Cold-pressed sunflower origin.
Non-GMO · Europe
Dr. Devin Ryerson
Founder & Chief Curator · Est. 1999Why It Matters
Built by someone with
personal stakes in it.
Devin started Pure Prescriptions in 1999 after battling Hodgkin's Lymphoma and losing his father to leukemia. That experience made him the most stubborn kind of formulator — one who refuses to ship anything he wouldn't take himself.
Every ingredient here earned its place through clinical evidence, third-party testing, and that same personal lens — the five collagen types, the organic fruiting-body mushrooms, the co-factors. Nothing is decorative.
"Pure Prescriptions has always been more personal than corporate. Built by family. Still independent."
Our StoryYour Journey
What to expect
CoQ10 works cumulatively at the cellular level. Here's what to expect.
WEEK 1–2
Energy Lift
Cellular ATP production begins to increase. Many users report improved stamina, reduced fatigue, and a noticeable lift in daily energy within the first two weeks.*
MITOCHONDRIAL SUPPORT
WEEK 4
Heart & Circulation
CoQ10 levels in blood plasma reach their optimal range. Cardiovascular tissue — the heart muscle in particular — begins receiving enhanced antioxidant protection.*
CARDIOVASCULAR SUPPORT
WEEK 8
Cognitive Clarity
Brain cells benefit from reduced oxidative stress. Users commonly report sharper focus, improved memory, and reduced mental fatigue during cognitively demanding tasks.*
COGNITIVE SUPPORT
WEEK 12
Full Cellular Defense
Sustained antioxidant defense across all tissues. The compounding benefit of consistent CoQ10 supplementation becomes measurable in energy, cognition, and heart health.*
FULL SPECTRUM BENEFIT
RESULTS ARE BEST WITH DAILY USE · MOST CUSTOMERS SEE FULL BENEFITS BY WEEK 12
Results vary from person to person.
The Mitochondrial Imperative
The supplement
most people over
40 aren’t taking.
“CoQ10 production in the body peaks in your mid-20s and declines steadily after that. By 50, most people are running on less than half their peak levels. And if you’re on a statin — which depletes CoQ10 as a known side effect — the deficit is even more significant.”
- 100 mg ubiquinol — the active, bioavailable form
- VESIsorb® self-emulsifying delivery technology
- Up to 6× greater absorption than standard CoQ10
- Non-GMO · Gluten-free · Soy-free · USA manufactured
The Morning Method
Have Questions?
Everything you need to know.
Honest answers — no marketing spin. If your question isn’t here, our team responds within one business day.
Ubiquinol is the active, reduced form of CoQ10 — the form your body uses in cellular energy production. The conventional form, ubiquinone, must be converted to ubiquinol before use. As we age, typically after 35, this conversion becomes less efficient, making direct ubiquinol supplementation a more direct form of CoQ10 support.
VESIsorb® is a patented self-emulsifying delivery system that converts CoQ10 into a colloidal dispersion in the GI tract — dramatically increasing surface area and absorption efficiency. Clinical studies show VESIsorb® delivers up to 6 times the blood levels of standard CoQ10 softgels at the same dose.
Adults over 35, individuals on statin medications, athletes seeking mitochondrial support, and those with cardiovascular health goals often consider CoQ10. If you use prescription medication or have a health condition, ask your healthcare professional whether CoQ10 belongs in your plan.
CoQ10 is fat-soluble, so take it with a meal containing some dietary fat. Morning or midday is preferred because it supports energy production throughout the day. Avoid taking late at night if energizing supplements tend to interfere with your sleep.
CoQ10 has a long history of study and is generally well tolerated for many adults. Our 100 mg ubiquinol dose is designed for daily use. If you are pregnant or nursing, use prescription medication, or have a specific health condition, consult your healthcare professional first.
Doctor’s Protocol
How I’d build your cardiovascular foundation.
“CoQ10 is the engine. Omega-3s support the membranes it energizes. Magnesium supplies the cofactors ATP uses. Mushrooms sustain the resilience that makes it last. Each is effective alone — together, they compound.*”
In Order of Priority
4 Products · 1 Protocol
Mitochondrial Energy · Cardiovascular
Bioactive Coenzyme Q10
Start here. Ubiquinol CoQ10 via VESIsorb® is the cornerstone of a mitochondrial or cardiovascular protocol — direct support every other stack layer builds upon.*
Heart & Omega-3 Support
Premium Omega-3 Plus
EPA/DHA supports oxidative balance and complements CoQ10's cardiovascular-support role at the cell membrane level — the natural second layer.*
ATP Cofactor · Recovery
Magnesium Glycinate
Magnesium is an essential cofactor in ATP synthesis — without it, the mitochondrial energy pathway CoQ10 supports is incomplete.*
Adaptogen · Resilience
Perfect Collagen + Mushroom Blend
Adaptogenic mushrooms support mitochondrial resilience under stress — the recovery and longevity extension of a CoQ10-anchored protocol.*
Add the full protocol — earn $25 store credit on your next order.
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Orders Shipped
Years in Business
Founded
Owned & Operated
In the USA
