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Methyl-Guard: A Foundational Formula for Healthy Methylation
Thorne’s Methyl-Guard is a foundational supplement designed to support the body’s crucial methylation pathway. This synergistic formula provides the active, tissue-ready forms of folate, vitamin B6, and vitamin B12, along with betaine (trimethylglycine). Proper methylation is essential for a wide range of bodily functions, from cardiovascular health and detoxification to neurotransmitter production. Methyl-Guard is a trusted choice for individuals seeking to support healthy homocysteine levels and promote overall wellness.
How It Works: The Power of Active B Vitamins and Betaine
This formula provides the key nutrients that act as “methyl donors,” which are required to fuel the methylation cycle.
Support for Cardiovascular and Neurological Health
Methyl-Guard is particularly effective at supporting the body’s process of converting homocysteine—a damaging amino acid when elevated—into the beneficial amino acid methionine. The active forms of Folate (5-MTHF), Vitamin B12 (methylcobalamin), and Vitamin B6 (P-5-P) are essential cofactors for this process. In addition, Betaine provides an alternate pathway for homocysteine metabolism, offering comprehensive support for cardiovascular health.
Promoting a Healthy Mood and Detoxification
A balanced methylation cycle is also vital for the synthesis of key neurotransmitters like serotonin and dopamine, making it fundamental to a positive mood. Furthermore, methylation is a key step in the liver’s detoxification pathways. By providing these essential nutrients, Methyl-Guard supports the body’s ability to process and eliminate toxins, making it a cornerstone formula for foundational health.
- ✅ Supports the body’s natural methylation cycle
- ✅ Helps maintain healthy homocysteine levels for cardiovascular wellness
- ✅ Contains the active, bioavailable forms of folate, B6, and B12
- ✅ Supports a positive mood and healthy neurotransmitter production
- ✅ Ideal for individuals needing methylation support, such as those with MTHFR variants
Product Ingredients
Supplement Facts:
Suggested Use: Take 3 capsules two times daily or as recommended by your health-care practitioner.
Serving Size: Three Capsules
Servings Per Container: 60
| Ingredient | Amount | %DV |
|---|---|---|
| Vitamin B6 (as Pyridoxal 5'-Phosphate) | 20.4 mg | 1,200% |
| Folate (1.2 mg as L-5-Methyltetrahydrofolate) from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt† | 2 mg DFE | 500% |
| Vitamin B12 (as Methylcobalamin) | 1.2 mg | 50,000% |
| Betaine Anhydrous (Trimethylglycine) | 1.8 g | ** |
Other ingredients: Hypromellose (derived from cellulose) capsule, Silicon Dioxide, Calcium Citrate, Calcium Laurate.
**Daily Value (DV) not established.
ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
PREGNANCY
If pregnant, consult your health-care practitioner before using this product.
INTERACTIONS
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, 5-MTHF has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
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Sincerely,
—Dr. Devin Ryerson
Founder & CEO
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