The Promise
Not all probiotics
are created equal.
Most probiotics don’t survive the journey to your gut. Digestive Defense™ uses an acid-resistant, shelf-stable, spore-forming strain proven to implant and thrive — with no bloating, no refrigeration required.
No Bloating or Gas
Formulated to implant without the digestive discomfort commonly associated with inferior probiotic strains. No adjustment period. No drama.
Clinically Studied Strain
Lactospore® (Bacillus coagulans) is selected based on peer-reviewed evidence for survivability through stomach acid and successful intestinal implantation.
100% Vegetarian
Fully plant-derived — no animal products, no artificial coatings, no unnecessary additives. Clean formulation from capsule to culture.
No Refrigeration
Shelf-stable technology ensures potency at room temperature — so your probiotic travels with you and works when you need it.
Why it Works
What your gut
can do for you.
01
Better Digestion
Balanced gut microflora supports efficient digestion and nutrient absorption, alleviating bloating, constipation, and irregularity.
02
Immune Defense
A significant portion of your immune system resides in your gut. Probiotics help fortify your body’s natural defenses against harmful pathogens.
03
Gut–Brain Axis
Emerging research links gut health to mood and cognitive function. Balanced microflora may reduce anxiety and support mental clarity.
04
Radiant Skin
Gut balance reduces systemic inflammation and improves toxin elimination — reflecting outward in clearer, healthier-looking skin.
Customer Reviews
Tried, tested,
truly loved.
YOUR PROTOCOL
Make it your method,
not just a habit
Digestive Defenseâ„¢ works best with intention. Hover each card to see the science behind the protocol.
MORNING
Take 1 capsule with your morning meal. Food helps buffer stomach acid and supports probiotic survival and implantation in the intestinal lining.*
WHY IT WORKS
Probiotics are most effective when introduced alongside food, which stabilizes gastric pH and provides substrate for bacterial metabolism.*
ANYTIME
Shelf-stable technology means Digestive Defense™ travels with you — no cold pack, no hassle. Consistency is everything with probiotics.
WHY IT WORKS
The spore-forming nature of Bacillus coagulans keeps the culture viable at room temperature, eliminating one of the biggest barriers to probiotic compliance.
POST-ANTIBIOTICS
Take 3 capsules daily for 2–4 weeks after completing an antibiotic course to help restore beneficial microflora and gut balance.*
WHY IT WORKS
Antibiotics eliminate both harmful and beneficial bacteria. Bacillus coagulans is a spore-forming probiotic studied for its ability to survive stomach acid and help re-establish healthy microflora after a course of antibiotics.*
HOW TO TAKE IT
Simple by design. Effective by science.
One capsule, three times daily with meals. That's the entire protocol — no stacking, no timing complexity.
What's Inside
What's inside,
and why it matters.
Bacillus coagulans (Lactospore®)
A spore-forming, lactic-acid-producing probiotic — formerly classified as Lactobacillus sporogenes. The spore coat shields the organism through stomach acid, then germinates in the intestine to support a healthy balance of microflora and normal gastrointestinal function.*
Patented Lactospore® · Spore-Forming
Bacillus coagulans (Lactospore®) · 2.25 billion friendly bacteria cells per capsule. View Supplement Facts →
Spore-Coat Survival
The protective spore coat keeps the culture viable at room temperature and resistant to gastric acidity. It survives transit, then swells and germinates once it reaches the intestine — delivering live organisms exactly where they are needed.*
Heat Stable · Gastric-Acid Resistant
Bacillus coagulans (Lactospore®) · 2.25 billion friendly bacteria cells per capsule. View Supplement Facts →
Rice Flour
A simple, hypoallergenic plant filler used to fill the capsule. The formula contains no dairy, wheat, yeast, corn, sugar, starch, soy, or preservatives — nothing that interferes with the culture.
Hypoallergenic · Allergen-Free
Bacillus coagulans (Lactospore®) · 2.25 billion friendly bacteria cells per capsule. View Supplement Facts →
100% plant-based. Zero compromise.
Hydroxypropyl methylcellulose — a plant-derived, shelf-stable capsule shell with no gelatin and no artificial coatings. Protects the probiotic culture during transit and dissolves cleanly in the intestine.
Plant-Derived · Shelf-Stable
Bacillus coagulans (Lactospore®) · 2.25 billion friendly bacteria cells per capsule. View Supplement Facts →
Dr. Devin Ryerson
Founder & Chief Curator · Est. 1999Why It Matters
Built by someone with
personal stakes in it.
Devin started Pure Prescriptions in 1999 after battling Hodgkin's Lymphoma and losing his father to leukemia. That experience made him the most stubborn kind of formulator — one who refuses to ship anything he wouldn't take himself.
Every ingredient here earned its place through clinical evidence, third-party testing, and that same personal lens — the five collagen types, the organic fruiting-body mushrooms, the co-factors. Nothing is decorative.
"Pure Prescriptions has always been more personal than corporate. Built by family. Still independent."
Our StoryThe Science
70% of your immune
system lives in your gut.
The gut-associated lymphoid tissue (GALT) is your body’s largest immune organ. A balanced microbiome doesn’t just support digestion — it helps train immune cells, supports a balanced inflammatory response, and communicates directly with the brain via the vagus nerve.*
Digestive Defenseâ„¢ delivers a spore-forming probiotic (Bacillus coagulans) selected for its ability to survive stomach acid, germinate in the intestine, and support a healthy balance of microflora and immune function.*
Digestion · Microflora · ImmuneCommon Questions
Frequently asked
questions.
Protocol Pairings
Better together.
Digestive Defense™ works best with intention. Hover each card to see the science behind the protocol.
In Order of Priority
4 Products · 1 Protocol
Pure Prescriptions
Digestive Defense™
Start here. Digestive Defense™ works best with intention as the probiotic foundation for this protocol.
Pure Prescriptions
Magnesium Glycinate
Magnesium supports gut motility and the relaxation of intestinal smooth muscle — a natural complement to probiotic balance.
Pure Prescriptions
Activated B-Complex
B vitamins are co-factors in the production of neurotransmitters influenced by gut bacteria — the gut-brain axis runs on both.
Pure Prescriptions
Curcumin C3 Complex
Curcumin reduces intestinal inflammation and supports the mucosal lining — creating a healthier environment for probiotic colonization.
Add the full protocol — earn $25 store credit on your next order.
Credited to your account · No code needed
Orders Shipped
Years in Business
Founded
Owned & Operated
In the USA
