Pure Encapsulations

Adenosyl/Hydroxy B12

$31.00

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The Promise

Focused B12 forms adenosyl + hydroxy combination

Two distinct, unmethylated B12 forms are provided together in each capsule.

Adenosylcobalamin included

Contains adenosylcobalamin, the mitochondrial form of vitamin B12.

Hydroxycobalamin included

Contains hydroxycobalamin, a precursor that converts to methylcobalamin and adenosylcobalamin in the body.

High single-capsule potency

Each vegetarian capsule supplies 2,000 mcg total vitamin B12.

Vegetarian delivery

Delivered in a vegetarian capsule made from cellulose and water.

Why It Works

Why these ingredients matter specific forms and roles

Each included B12 form has a distinct biochemical role that informed the combination.

01

Mitochondrial storage

Adenosylcobalamin is the major form of B12 stored in mitochondria of cellular tissues.

02

Cofactor for metabolism

Adenosylcobalamin is a key cofactor for methylmalonyl-CoA mutase used to produce succinyl-CoA in carbohydrate metabolism.

03

Precursor versatility

Hydroxycobalamin converts to both methylcobalamin and adenosylcobalamin, offering precursor flexibility.

04

Unmethylated B12 strategy

The product provides unmethylated B12 forms rather than methylcobalamin alone.

Reviews

Customer Reviews

Your Journey

How to use it simple, label-supported directions

Follow the stated serving range and capsule format for practical daily use.

Serving size

Take 1 capsule per serving

Suggested use is 1 capsule, 1–3 times daily with meals.

Timing with meals

Take with food

Take each capsule with a meal as part of the suggested regimen.

Capsule format

Vegetarian capsule material

Capsules are vegetarian and consist of cellulose and water.

Dose considerations

Adjust within the recommended range

Daily intake can be one to three capsules to match the suggested 1–3 times daily guidance.

Product education

Suggested Use: 1 capsule, 1-3 times daily, with meals.

Adenosyl/Hydroxy B12 – Unique blend of adenosylcobalamin and hydroxycobalamin offers unmethylated B12 to promote nerve and mitochondrial health.*
Hydroxycobalamin is a precursor form of vitamin B12 converted in the body to both methylcobalamin and adenosylcobalamin. It is similar to cyanocobalamin without the cyanide moiety. Adenosylcobalamin is an activated form similar to methylcobalamin. While methylcobalamin is found in the cytosol of cells and predominates in blood and other fluids, adenosylcobalamin is the major form of vitamin B12 stored in the mitochondria of cellular tissues. It is a key cofactor in carbohydrate metabolism for the enzyme methylmalonyl-CoA mutase used to produce succinyl-CoA. Optimal levels also support healthy synthesis of neuronal myelin.*

Supplement record

Review serving details and ingredients for this product.

Supplement Facts:
Suggested Use: 1 capsule, 1-3 times daily, with meals.
each vegetarian capsule contains:
Ingredients AMT %DV
Vitamin B12 (as adenosylcobalamin and 50% hydroxycobalamin) 2,000 mcg -
Other Ingredients: vegetarian capsule (cellulose, water)
(-) There is no %DV or the manufacturer has not provided this data.