Pure Encapsulations

Ubiquinol-QH

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The Promise

Active Ubiquinol CoQ10 — ready-to-use antioxidant

Ubiquinol-QH provides the reduced, active antioxidant form of CoQ10 (ubiquinol) in softgel form.

Form and strengths

Available in 50 mg, 100 mg, and 200 mg softgels, with 60 softgels per bottle for each strength.

Principal ingredient

Contains Kaneka Ubiquinolâ„¢ as the active antioxidant form of coenzyme Q10.

Softgel delivery and excipients

Formulated as an oil-based softgel using medium chain triglycerides, sunflower lecithin, beeswax, annatto extract, gelatin capsule and glycerin.

Quality and sourcing notes

CoQ10 is produced via microbial (yeast) fermentation; medium chain triglycerides are palm-derived and ascorbyl palmitate is derived from corn dextrose fermentation and palm oil.

Why It Works

Why ubiquinol matters — form, absorption, and biological role*

This product uses ubiquinol specifically and includes formulation choices that support oil-based delivery.*

01

Predominant plasma form in younger adults

Ubiquinol makes up over 90% of the CoQ10 pool in the plasma of healthy young individuals up to about age 40–45.

02

Active antioxidant chemistry

Ubiquinol is the reduced form of CoQ10 with two additional hydrogen atoms and represents the active antioxidant form.

03

Conversion step in energy production

The enzymatic conversion between ubiquinone and ubiquinol occurs in mitochondria as a key step in the electron transport chain and ATP manufacture.

04

Formulation tied to bioavailability*

Ubiquinol has shown significant gastrointestinal absorption in single-dose and 4-week multiple-dose studies and may be more readily absorbed than ubiquinone.*

Reviews

Customer Reviews

Your Journey

How to use — serving, timing, and precautions

Follow these practical points for daily use, suitability, and clinician considerations.

Serving

Daily softgel intake

Take 1 softgel per day with a meal; recommended intake can be 1–2 softgels daily with meals.

Strength selection

Choose a dose that fits your needs

Available in 50 mg, 100 mg, and 200 mg strengths so you can select the milligram amount you and your health professional prefer.

Dietary and format considerations

Softgel ingredients to note

Softgel contains bovine-derived gelatin and palm-derived medium chain triglycerides, and uses sunflower lecithin and ascorbyl palmitate.

Precautions

When to consult a clinician

If pregnant or lactating consult a physician before use; consult a clinician if taking blood-thinning medication due to potential contraindication.

Product education

Suggested Use: Take 1 softgel per day with a meal, or as directed by a health professional.

Ubiquinol-QH – Older adults may benefit from supplementing this particular form of COQ10. Ubiquinol is known to be the active antioxidant form of CoQ10. Ubiquinol can be especially helpful for older adults, or those under greater oxidative or physical stress. This form has also shown important results for those who appeared not to respond to other forms of CoQ10. The mainstay for cellular mitochondrial energy, CoQ10 is often recommended by health professionals to be taken for over all health and vitality.

What Is It?

Ubiquinol is the active antioxidant form of CoQ10. It has an additional two hydrogen atoms and compromises the majority of the ubiquinone/ubiquinol pool in the plasma of healthy young subjects. In the body, the enzymatic conversion of ubiquinone to ubiquinol in the mitochondria is a key step in the electron transport chain and the manufacture of ATP.*

Uses For Ubiquinol-QH

General Support: *

Ubiquinol makes up over 90% of the CoQ10 found in the plasma of healthy young individuals, typically up to the age of about 40-45 years. This makes ubiquinol especially important for older individuals, individuals who may be experiencing greater levels of oxidative or physical stress, or individuals who appear not to respond to regular CoQ10 supplementation (possibly due to poor conversion of CoQ10 to ubiquinol in the body). Research suggests that it may be more readily absorbed than the ubiquinone form. The safety and bioavailability of ubiquinol were evaluated after single oral dose and 4-week multiple dose studies. Significant gastrointestinal absorption was observed and no clinically significant adverse effects were noted.*

Cardiovascular Support:*

In a preliminary case report involving an open clinical evaluation using ubiquinol, a U.S. cardiologist reports that plasma CoQ10 levels doubled for one 52 year-old woman after supplementation with 300 mg ubiquinol in divided doses for one month. It was also noted that ubiquinol supported a healthy ratio of CoQ10 to lipids. In a separate case, a 65 year-old male not responding to CoQ10 supplementation experienced a 4-fold increase in plasma CoQ10 after supplementation with the same dose of ubiquinol. In addition, ubiquinol supported healthy ejection fraction and mitral valve function while supporting overall physical activity and quality of life.*

What Is The Source?

CoQ10 is produced by microbial (yeast) fermentation. There is no residual yeast in the final product. Medium chain triglycerides are derived from palm oil. Gelatin is bovine-derived. Lecithin is derived from sunflower. Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil. Kaneka QHâ„¢ is a trademark of Kaneka Corporation. The use of ascorbyl palmitate in the formulation is covered by U.S. Patent 6,740,338.

Recommendations

Pure Encapsulations recommends 1–2 softgels daily with meals.

Are There Any Potential Side Effects Or Precautions?

Rarely, CoQ10 may cause mild gastrointestinal upset, nausea, vomiting, diarrhea or constipation. If pregnant or lactating, consult your physician before taking this product.

Are There Any Potential Drug Interactions?

CoQ10 may be contra-indicated for individuals taking blood thinning medication. Consult your physician for more information.

Supplement record

Review serving details and ingredients for this product.

Supplement Facts:
Suggested Use: Take 1 softgel per day with a meal, or as directed by a health professional.
each softgel capsule contains:
Ingredients AMT %DV
Kaneka Ubiquinolâ„¢ (active antioxidant form of coenzyme Q10) 50 mg -
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Kaneka Ubiquinolâ„¢ (active antioxidant form of coenzyme Q10) 100 mg -
- -
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Kaneka Ubiquinolâ„¢ (active antioxidant form of coenzyme Q10) 200 mg. -
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Other Ingredients: medium chain triglycerides, gelatin capsule (gelatin, glycerin, water), ascorbyl palmitate, sunflower lecithin, beeswax, annatto extract in sunflower oil
(-) There is no %DV or the manufacturer has not provided this data.