Ther-Biotic InterFase Plus - Enzyme and EDTA formula for biofilm disruption.
Ther-Biotic InterFase Plus - Enzyme and EDTA formula for biofilm disruption.

Klaire Labs/SFI Health

Ther-Biotic® Interfase Plus

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The Promise

Product Identity & Key Facts Enzyme‑based biofilm support with chelator*

Ther‑Biotic® InterFase® Plus — proprietary enzyme blend plus EDTA in vegetarian capsules; hypoallergenic profile with egg-derived lysozyme.

What it is

A targeted enzyme formulation designed to disrupt gastrointestinal biofilm matrices (InterFase® Plus) in an enteric‑ready capsule format.

Principal ingredients & forms

675 mg proprietary enzyme blend per 2‑capsule serving: polysaccharide‑specific enzymes (glucoamylase, chitosanase, cellulase, hemicellulase/pectinase, beta‑glucanase), protease/peptidase complex (including DPP‑IV activity), lysozyme (egg white), and enteric‑coated Serratia peptidase (Peptizyme SP®).

Chelator included

Disodium EDTA (30 mg per 2 capsules) included to bind metals (e.g., calcium, iron, magnesium) implicated in biofilm structural integrity.

Dietary & quality facts

Vegetarian HPMC capsules; free of milk/casein, fish, shellfish, tree nuts, peanuts, wheat, soy, and gluten; contains egg; no artificial colors, flavors, or preservatives.

Why It Works

Why this formulation is distinct Specific enzyme spectrum plus metal chelation and enteric delivery

Combines multiple enzyme specificities, EDTA chelation, and an enteric‑coated protease to target different biofilm components and access intestinal environments.

01

Broad polysaccharide digestion

Includes polysaccharide‑specific enzymes (glucoamylase with isomaltase side‑chain, chitosanase, cellulase, hemicellulase/pectinase, beta‑glucanase) to degrade carbohydrate components of biofilms.

02

Protein and peptide targets

Protease/peptidase complex provides endopeptidase, exopeptidase, and DPP‑IV activity to cleave protein and peptide constituents of the matrix.

03

Enteric‑coated Serratia peptidase

Serratia peptidase (Peptizyme SP®) is provided in an enteric‑coated form to protect activity until intestinal release.

04

EDTA metal chelation

Disodium EDTA (30 mg per serving) binds metals such as calcium, iron, and magnesium that contribute to biofilm stability, complementing enzymatic breakdown.

Reviews

Customer Reviews

Your Journey

How to use & important precautions Dosing windows, format, storage, and contraindications

Follow labeled dosing and warnings; take capsules away from meals to maximize enzyme activity and consult a healthcare practitioner when indicated.

Serving & timing

Adults: typical dosing

Take 2 capsules, 1 to 4 times daily between meals, depending on age and size, or as directed by a healthcare practitioner.

Form & administration

Capsule format

Vegetarian (HPMC) capsules; take away from meals to maximize enzyme effectiveness.

Storage & allergens

Allergy & storage notes

Contains egg (lysozyme). Free of common allergens listed on label. KEEP OUT OF REACH OF CHILDREN.

Warnings & practitioner considerations

Contraindications & medical review

Not for long‑term daily use. Do not use if pregnant or nursing, have kidney or liver condition, or are under 18. If you have any medical condition or take prescription drugs, consult your physician before use.

Product education

Ther-Biotic® InterFase® Plus: Enhanced Biofilm Disruption

Ther-Biotic® InterFase® Plus is a unique enzyme formulation with EDTA, specifically designed to disrupt the biofilm matrix that can embed gastrointestinal organisms. Biofilms are protective encasements formed by microorganisms, making them highly resistant to antimicrobials. This powerful formula combines a proprietary blend of enzymes that degrade bacterial and yeast cell wall structures with EDTA, which binds the metals necessary for biofilm formation, encouraging a healthy intestinal microbial community.

How It Works: A Dual-Action Approach to Biofilm

This supplement provides a unique combination of enzymes and a key chelating agent to effectively break apart the protective structure of biofilms.

A Proprietary Enzyme Blend
InterFase® Plus features a comprehensive blend of enzymes with a wide range of targets. Polysaccharide-specific enzymes like cellulase and beta-glucanase break down the carbohydrate structure of the biofilm, while protein- and peptide-specific enzymes like the DPP-IV complex degrade the protein components. It also includes lysozyme and the enteric-coated enzyme Serratia peptidase for enhanced activity.

Enhanced with EDTA for Maximum Activity
The formation of biofilm requires metals like calcium, iron, and magnesium to create its structure. This formula includes EDTA (ethylenediaminetetraacetic acid), which binds these essential metals. This action weakens the biofilm’s integrity and enhances the ability of the enzymes to break it down, providing maximum anti-biofilm activity.

  • A unique enzyme formula designed to disrupt the biofilm matrix
  • Enhanced with EDTA to bind metals needed for biofilm formation
  • Helps degrade bacterial and yeast cell wall structures*
  • Encourages a healthy intestinal microbial community
  • A clean, hypoallergenic formula free of common allergens

Supplement record

Review serving details and ingredients for this product.

Supplement Facts:
Suggested Use: Adults: Depending on age and size, take 2 capsules, 1 to 4 times daily between meals or as directed by a healthcare practitioner. The capsules should be taken away from meals to maximize enzyme effectiveness. Children: As directed by a healthcare professional.
Serving Size: 2 Capsules
Servings Per Container: 30
Ingredient Amount %DV
Sodium (as disodium EDTA) 30 mg 1%
Proprietary Enzyme Blend with EDTA 675 mg *
Polysaccharide Specific Enzymes
Glucoamylase (with isomaltase side chain activity)
Chitosanase, Cellulase,Hemicellulase/Pectinase Complex, Beta-Glucanase
Protein and Peptide Specific Enzymes
Protease/Peptidase Complex with endopeptidase, exopeptidase, and DPP-IV activity
Other Enzymes
Lysozyme (from egg white)
Serratia peptidase (from Serratia marcescens)(enteric-coated)(Peptizyme SP®‡)
EDTA (as disodium EDTA)
Other Ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), ascorbyl palmitate, and microcrystalline cellulose.
*Daily Value not established.
Warning This product is not intended for long-term daily use. Do not use this product if you are pregnant or nursing, have a kidney or liver condition or are below the age of 18. If you have any other medical condition, or if you are taking prescription drugs, consult your physician before using this product. KEEP OUT OF REACH OF CHILDREN.
Allergy Information Contains Egg. Free of the following common allergens: milk/casein, fish, shellfish, tree nuts, peanuts, wheat, soy, and gluten. Contains no artificial colors, flavors, or preservatives. Consult your physician before use if you are allergic to eggs or coconut.

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