Pure Encapsulations

Synergy K

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The Promise

Complete Vitamin K spectrum — K1 plus K2 (MK‑4 & MK‑7) and vitamin D3

A multiform vitamin K formula that supplies phylloquinone, menaquinone‑4 and menaquinone‑7 together with vitamin D3.

Three types of vitamin K

Provides vitamin K1 (phylloquinone), vitamin K2 as MK‑4 (menaquinone‑4) and MK‑7 (menaquinone‑7) in a single capsule.

Includes vitamin D3

Each capsule supplies 1,000 IU cholecalciferol alongside the K complex for combined nutrient support.*

High‑potency K amounts

Total vitamin K per capsule is 1,545 mcg, with 500 mcg K1, 1,000 mcg MK‑4 and 45 mcg MK‑7.

Hypo‑allergenic capsule fill

Uses plant‑derived hypo‑allergenic fiber (pine cellulose) as the non‑active capsule filler.

Why It Works

Why this combination matters — Different K forms have distinct tissue distribution and persistence

The formula combines forms that concentrate differently in the body and have different half‑lives to broaden tissue availability.

01

K1 and MK‑4 target the liver

Phylloquinone and MK‑4 are primarily concentrated in the liver, which supports hepatic vitamin K pools.*

02

MK‑7 reaches extra‑hepatic tissues

MK‑7 is concentrated in extra‑hepatic tissues, including vascular tissues, and has a longer half‑life than other forms.

03

D3 potentiates K activity

Vitamin D3 supports the synthesis of vitamin K–dependent bone proteins and potentiates matrix Gla‑protein activity.*

04

Broad spectrum for calcium utilization

Combining K1, MK‑4, MK‑7 and D3 supports processes involved in healthy calcium handling in bone and vascular tissues.*

Reviews

Customer Reviews

Your Journey

How to Use — Dosing and storage

Follow recommended servings and store as you would other capsules.

Serving

Take 1–2 capsules daily

Suggested use is 1 to 2 capsules per day, taken in divided doses with meals.

Timing with meals

Take with food

This product is intended to be taken with meals to align with fat‑soluble vitamin intake.

Safety considerations

Not for those on warfarin or pregnant/lactating

Do not use while taking Coumadin/warfarin or if pregnant or breastfeeding; consult a physician if on dialysis or taking other medications.

Package options

Available capsule counts

Comes in 60‑count or 120‑count vegetable capsules; each capsule contains plant fiber as filler.

Product education

Suggested Use: 1-2 capsules per day, in divided doses, with meals. Not to be taken by pregnant or lactating women. Not for individuals taking blood thinning medications.Vitamin K supplementation is contraindicated for those taking Coumadin/warfarin anticoagulant medication.

Synergy K – Vitamin K also known as phylloquinone, is a fat soluble vitamin found in many foods, including natto, alfalfa, dark leafy greens and fish oils. Vitamin K is necessary for proper blood clotting and coagulation. Pure Encapsulations Synergy K, is a complete formula providing all 3 types of Vitamin K, including the forms that are naturally occurring in our own gut. This supplement is contraindicated for those on anticoagulant protocols.

What Is It?

Vitamin K includes a group of compounds that contain a central ring structure with varying side chains. These differing side chains account for differences in absorption, bioavailability, transport and tissue distribution. Vitamin K1, phylloquinone, is the most common form and is found in plants and green vegetables. The vitamin K2 family, menaquinones, are less common and are found in meats, eggs, some cheeses, and fermented food, such as Japanese natto. The most common menaquinones are menaquinone-4 (MK-4) and menaquinone-7 (MK-7). Studies indicate that vitamin K1 and MK–4 are primarily concentrated in the liver, while MK–7 is concentrated in extra–hepatic tissues, including vascular tissues. MK-7 also has a longer half–life. This unique formula contains a broad-spectrum blend of vitamins K1, K2 and D for healthy calcium utilization to maintain healthy bones and blood vessels.*

Uses For Synergy K

Bone Health:

Vitamin K enhances bone formation by carboxylating osteocalcin. This enables osteocalcin to bind to calcium and promote healthy bone mineralization. Vitamin D synergistically regulates the synthesis of osteocalcin by osteoblasts in bone. Adequate intake of vitamin K1 and K2 may be especially important for optimal carboxylation in aging individuals, as indicated by a recent study involving Japanese women.*

Vascular Health:

Vitamin K dependent proteins in the liver are responsible for maintaining healthy blood coagulation and platelet function. Additionally, by activating matrix Gla-protein (MGP), vitamin K also helps maintain healthy calcium metabolism in vascular tissues, supporting healthy vascular elasticity. Recent studies indicate that vitamin D potentiates the activity of MGP and that the combination of vitamin K and D provides synergistic support for blood vessel function.*

What Is The Source?

Vitamin K 1 and vitamin K 2 (menaquinone-4) are synthetic. Vitamin K 2 (MK-7) is naturally derived from flower extracts geraniol and farnesol. Vitamin D 3 is derived from lanolin. Hypo-allergenic plant fiber is derived from pine cellulose.

† is a trademark of NattoPharma, Norway.

Recommendations

Pure Encapsulations recommends 1–2 capsules per day, with a meal.

Are There Any Potential Side Effects Or Precautions?

Vitamin K may be contraindicated for individuals on dialysis treatment. Not to be taken by pregnant or lactating women. Consult your physician for more information.

Are There Any Potential Drug Interactions?

Vitamin K is contra-indicated for individuals taking Coumadin/warfarin blood thinning medication. Consult your physician for more information.

For educational purposes only. Consult your physician for any health problems. *These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Supplement record

Review serving details and ingredients for this product.

Supplement Facts:
Suggested Use: 1-2 capsules per day, in divided doses, with meals. Not to be taken by pregnant or lactating women. Not for individuals taking blood thinning medications.Vitamin K supplementation is contraindicated for those taking Coumadin/warfarin anticoagulant medication.
each vegetable capsule contains:
Ingredients AMT %DV
vitamin D3 ( as cholecalciferol ) ( D3) 1000 i.u. -
vitamin K: 1,545 mcg. -
vitamin K1 500 mcg -
vitamin K2 (menaquinone-4) 1,000 mcg -
vitamin K2 (menaquinone-7) 45 mcg -
Other Ingredients: (hypo-allergenic plant fiber added to complete capsule volume requirement)
(-) There is no %DV or the manufacturer has not provided this data.