Suggested Use: 2 capsules per day, in the morning, with a meal.
What Is It?
PQQ (pyrroloquinoline quinone) is a novel cofactor with antioxidant and B vitamin-like activity. It is naturally present in vegetables and in the human body, including breast milk, and posseses unique neuroprotectant and cardioprotectant properties. MicroActive CoQ10 is a water-soluble, submicron particle-sized CoQ10 generated using a patented process that complexes each CoQ10 molecule with a beta-cyclodextrin molecule. CoQ10 is bound to the lipophilic end of the molecule, while the other end is hydrophilic, facilitating dispersion and transport. At the cellular surface, the complex dissociates, liberating a single CoQ10 molecule for efficient absorption. The extended 24-hour release of MicroActive® CoQ10 also allows for convenient, once-daily dosing. Clinical research indicates superior absorption compared to solubilized and crystalline CoQ10, with low inter-subject variance.* Figure 1. SR-CoQ10 absorption in human volunteers. Comparison of the mean plasma CoQ10 concentrations after a single oral dose of either SR-CoQ10 or solubilized softgel CoQ10.
Uses For SR-CoQ10 with PQQ
PQQ and CoQ10 provide antioxidant and mitochondrial support through different mechanisms, providing multifunctional support for cardiovascular health. Research indicates that both PQQ and CoQ10 support heart muscle function and healthy cellular oxygen utilization. However, the mechanisms for this support differ. Studies suggest that PQQ promotes mitochondrial synthesis and function, while CoQ10 promotes energy production as a core component of cellular respiration. These actions are particularly supportive of tissues that require a lot of energy, such as the heart muscle. Furthermore, they acts as antioxidants, providing protection from free-radicals and helping to maintain the integrity of cellular membranes.* Nerve and Cognitive Health: Numerous studies have indicated that PQQ supports nerve health. Mechanistic investigations suggest that PQQ supports several signal transduction pathways that are important in maintaining mitochondrial homeostasis and oxidative metabolism. Like CoQ10, PQQ is a powerful antioxidant that supports mitochondrial function. PQQ also supports healthy levels of nerve growth factor and glutamate receptor activity. Several studies suggest that PQQ may promote learning ability and memory. In a double-blind, placebocontrolled clinical trial conducted in 71 middle-aged individuals, PQQ supplementation over a 12 week period supported healthy cognitive performance, and a combination of PQQ and CoQ10 provided greater support than PQQ alone.*
What Is The Source?
BioPQQ™ pyrroloquinoline quinone disodium salt is manufactured in Japan using a patented natural fermentation process. It contains 2.7 mg sodium per capsule. MicroActive® CoQ10-cyclodextrin complex (SR-CoQ10) contains coenzyme Q10 obtained naturally from fermentation and potato starch. Hypo-allergenic plant fiber is derived from pine cellulose.
Pure Encapsulations recommends 2 capsules daily, in the morning, with a meal.
For educational purposes only. Consult your physician for any health problems.
Are There Any Potential Side Effects Or Precautions?
If pregnant or lactating, consult your physician before taking this product. At this time, there are no known side effects or precautions. Consult your physician for more information.
Are There Any Potential Drug Interactions?
CoQ10 may react with blood thinning medications. Consult your physician for more information.