Thorne Pro-Resolving Mediators - SPM supplement for inflammation resolution, immune function, and brain health.
Thorne Pro-Resolving Mediators - SPM supplement for inflammation resolution, immune function, and brain health.
Thorne Pro-Resolving Mediators - SPM supplement for inflammation resolution, immune function, and brain health.

Thorne Research

Pro-Resolving Mediators

$75.00

SIZE: 60 Capsules

*Free shipping applies to orders shipped within the Lower 48 States.


Free shipping on orders over $99.
SKU: T13365 Categories: , , Tags: , , Product Brand:

The Promise

Identity, formulation, and quality Concentrated pro-resolving mediators in a single daily gelcap

Finished specialized pro-resolving mediators (SPMs) delivered as a refined marine oil gelcap with defined omega‑3 content and standard excipients.

Product identity

Pro‑Resolving Mediators (Thorne Research) — a marine lipid concentrate gelcap supplying finished SPMs (18‑HEPE, 17‑HDHA, 14‑HDHA).

Principal ingredients & amounts

One gelcap contains 650 mg Marine Lipid Concentrate (providing 300 mcg SPMs), 500 mg total omega‑3s, 250 mg DHA and 160 mg EPA.

Formulation & delivery

Highly refined concentrated marine oil in a bovine gelatin glycerin purified‑water gelcap; mixed tocopherols included as antioxidants.

Dietary & allergen facts

Contains ingredients derived from fish and/or shellfish (anchovy, sardine, squid, herring, mackerel).

Why It Works

Why this formula is distinct Direct provision of finished SPMs and measured omega‑3s in a refined marine oil base

Concrete formulation choices that bypass conversion and specify species, amounts, and delivery form.

01

Finished SPMs included

Provides 300 mcg of specialized pro‑resolving mediators specifically listing 18‑HEPE, 17‑HDHA and 14‑HDHA.

02

Measured EPA/DHA content

Delivers 250 mg DHA and 160 mg EPA per gelcap for known omega‑3 dosing transparency.

03

Concentrated marine lipid source

Marine Lipid Concentrate (650 mg) supplies both SPMs and total omega‑3s in a single refined oil matrix.

04

Capsule and excipients

Gelcap uses bovine gelatin, vegetable‑source glycerin and purified water; mixed tocopherols present as preservative.

Reviews

Customer Reviews

Your Journey

How to use & safety Serving, storage, contraindications and practitioner considerations

Clear labeled directions plus authoritative warnings and interaction notes.

Serving

Suggested use

Take 1 gelcap daily or as recommended by your health‑care practitioner. Serving size: one gelcap; 30 servings per container.

Format & storage

Format and ingredients to note

Single refined marine oil gelcap containing gelatin (bovine), glycerin, purified water and mixed tocopherols; store per container labeling.

Allergy & pregnancy

Allergy and pregnancy guidance

Contraindicated with hypersensitivity to any ingredients; contains fish/shellfish. If pregnant, consult your health‑care practitioner before use.

Interactions & cautions

Medication interaction warning

As with any fish oil product, use with caution or avoid if on anticoagulant therapy.

Product education

Pro-Resolving Mediators: An Advanced Formula for Inflammation Resolution

Thorne’s Pro-Resolving Mediators is a cutting-edge nutritional supplement that provides a concentrated source of specialized pro-resolving mediators (SPMs). This advanced formula goes beyond standard fish oil to deliver the downstream metabolites that act as the body’s natural “stop signals” for the inflammatory response. By actively helping to resolve inflammation, SPMs support tissue repair and help the body return to a healthy state of balance, or homeostasis. It is an ideal choice for supporting brain, nerve, and immune health.*

How It Works: The “Braking System” for Inflammation

A healthy inflammatory response is essential, but it’s equally important for it to resolve in a timely manner. SPMs are the key signaling molecules that facilitate this resolution process.

Beyond Standard Omega-3s
While the body can convert omega-3s like EPA and DHA into SPMs, this process can be inefficient. This formula provides a concentrated source of these finished pro-resolving mediators, including 18-HEPE, 17-HDHA, and 14-HDHA. Providing SPMs directly bypasses the need for conversion, offering a more targeted and efficient approach to supporting the body’s natural inflammation resolution pathways.*

Supporting a Return to Homeostasis
Instead of simply blocking inflammation, SPMs work to actively clean up the aftermath of the inflammatory response and support the healing of damaged tissues. This process is crucial for maintaining the health of the brain and nerves, promoting a balanced immune response, and supporting overall systemic wellness. This makes Pro-Resolving Mediators a next-generation approach to managing the body’s inflammatory processes.*

  • Provides concentrated Specialized Pro-Resolving Mediators (SPMs)
  • Supports the natural resolution of the inflammatory response*
  • Promotes the healing and repair of damaged tissues*
  • Supports brain, nerve, and immune system health*
  • A more targeted approach than standard fish oil for inflammation support*

Supplement record

Review serving details and ingredients for this product.

Supplement Facts:
Suggested Use: Take 1 gelcap daily or as recommended by your health-care practitioner.
Serving Size: One Gelcap
Servings Per Container: 30
Ingredient Amount %DV
Calories 10
Total Fat 1 g 1%*
Cholesterol 5 mg 2%*
Marine Lipid Concentrate (from Fish Oil) 650 mg **
[providing 300 mcg of Pro-Resolving Mediators including 18-hydroxyeicosapentaenoic acid (18-HEPE), 17-hydroxydocosahexaenoic acid (17-HDHA), and 14-hydroxydocosahexaenoic acid (14-HDHA)]
Total Omega-3 Fatty Acids (from Fish Oil) 500 mg **
DHA (Docosahexaenoic Acid) 250 mg **
EPA (Eicosapentaenoic Acid) 160 mg **
Other ingredients: Highly Refined Concentrated Marine Oil, Gelatin (bovine), Glycerin (vegetable source) and Purified Water gelcap, Mixed Tocopherols.
*Percent Daily Values are based on a 2,000 calorie diet.
**Daily Value (DV) not established.
ALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. Contains ingredients derived from fish and/or shellfish (fish oil = anchovy, sardine, squid, herring, mackerel).
PREGNANCY If pregnant, consult your health-care practitioner before using this product.
INTERACTIONS As with any fish oil product, this product should be used with caution or avoided in individuals on anticoagulant therapy.

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