Life Extension

Optimized Folate (L-Methylfolate)

$15.00

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The Promise

What this is Bioactive 5‑MTHF folate in a single daily tablet

Provides metabolically active folate to support normal folate status and homocysteine maintenance.*

Identity

Optimized Folate (Life Extension) — vegetarian tablet delivering 5‑Methyl­tetrahydrofolate.

Principal ingredient & amount

Contains 1,700 mcg DFE as (6S)-5‑Methyl­tetrahydrofolate, calcium salt per tablet.

Formulation & delivery

Single daily vegetarian tablet; other ingredients: microcrystalline cellulose, dicalcium phosphate, croscarmellose sodium, silica, vegetable stearate, stearic acid.

Dietary & quality facts

Non‑GMO; packaged with tamper-evident seal. Do not purchase if outer seal is broken or damaged.

Why It Works

Why this formulation Concrete formulation choices that affect absorption and use*

Key facts on form, dose, combinations, and intended biochemical role.

01

Direct bioactive form

Delivers (6S)-5‑MTHF, the metabolically active form of folate that bypasses conversion steps required for folic acid.

02

Therapeutic daily dose

Provides 1,700 mcg DFE of 5‑MTHF per tablet—specified single‑tablet daily amount.

03

Combination compatibility

Label notes combined use with methylcobalamin (B12), vitamin B6, or riboflavin may further support folate‑related biochemical pathways.*

04

Vegetarian tablet format

Tablet form with standard excipients for stability and oral delivery; suitable for vegetarian diets.

Reviews

Customer Reviews

Your Journey

How to use Clear directions, precautions, and storage notes

Practical serving, timing, and safety information from the label.

Serving

Suggested use

Take one (1) tablet daily with food, or as recommended by a healthcare practitioner.

Timing & format

Take With Food

One vegetarian tablet per day; swallow with food to reduce gastrointestinal upset.

Warnings

Clinical cautions

Consult your healthcare provider if at risk of B12 deficiency; high‑dose folate can mask B12 deficiency. Consult your physician if treating a medical condition or if pregnant or lactating. KEEP OUT OF REACH OF CHILDREN. DO NOT EXCEED RECOMMENDED DOSE.

Packaging & storage

Seal & purchase guidance

Do not purchase if outer seal is broken or damaged.

Product education

Optimized Folate – 5‑MTHF for Heart & Brain Health

What Is Optimized Folate?

Maintaining normal homocysteine levels is linked to cardiovascular and cognitive health. Optimized Folate delivers 1,700 mcg of metabolically active 5‑Methyl­tetrahydrofolate (5‑MTHF), bypassing conversion limitations to support healthy folate levels.*

Optimized Folate Benefits*

  • Supports cardiovascular and cognitive health*
  • Helps maintain already‑healthy homocysteine levels*
  • Delivers 1,700 mcg bioactive folate per day

Product Details

As a key B‑vitamin, folate plays a central role in neurotransmitter synthesis and enzymatic reactions throughout the body. Because many people lack the enzyme needed to convert folic acid into active folate, delivering 5‑MTHF ensures optimal absorption and efficacy.*

1,700 mcg of 5‑MTHF supports healthy homocysteine levels, promoting cardiovascular system function and cognitive resilience—especially important for aging individuals or those with genetic metabolic impediments. When used with methylcobalamin (B12), B6, or riboflavin, benefits may be further enhanced.*

Supplement record

Review serving details and ingredients for this product.

Supplement Facts:
Suggested Use: Take one (1) tablet daily with food, or as recommended by a healthcare practitioner.
Serving Size: 1 vegetarian tablet
Ingredients Amount %DV
Folate [as (6S)-5‑Methyl­tetrahydrofolate, calcium salt] 1,700 mcg DFE°
Other ingredients: Microcrystalline cellulose, dicalcium phosphate, croscarmellose sodium, silica, vegetable stearate, stearic acid.
Non‑GMO
Caution: Consult your healthcare provider if at risk of B12 deficiency, as high-dose folate may mask deficiency.
Warning: KEEP OUT OF REACH OF CHILDREN. DO NOT EXCEED RECOMMENDED DOSE. Do not purchase if outer seal is broken or damaged. Consult your physician if treating a medical condition or if pregnant or lactating.