Pure Encapsulations

NSK–SD™ (Nattokinase)

Price range: $82.00 through $152.50

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The Promise

What this is — NSK–SD™ nattokinase

A nattokinase enzyme formula isolated from natto designed to support normal fibrinolytic activity.*

Core ingredient and potency

Each capsule provides nattokinase 100 mg standardized to 2000 FU of fibrinolytic activity.

Complementary ingredient

Contains 5 mg vitamin C as ascorbyl palmitate per capsule to complete the formulation.

Vegetarian delivery

Supplied in a vegetable capsule with hypo‑allergenic plant fiber used to fill the capsule volume.

Tradition and sourcing

Nattokinase is isolated from natto produced by fermentation with Bacillus natto (Bacillus subtilis natto).

Why It Works

Why this formulation matters — enzyme form and potency

Key formulation details explain how nattokinase supports normal fibrinolytic processes and circulation.*

01

Fibrinolytic enzyme function

Nattokinase is a fibrinolytic enzyme that can support the body's natural fibrinolysis by acting on fibrin.*

02

Mechanisms observed

Research indicates nattokinase may inactivate plasminogen activator inhibitor and directly degrade fibrin to support healthy clotting balance.*

03

Source organism specified

The enzyme is derived from natto produced using Bacillus natto (Bacillus subtilis natto), the traditional fermentation strain.

04

Potency unit provided

Activity is expressed in fibrinolytic units (2000 FU per capsule), which denotes the product's enzymatic fibrinolytic potency.

Reviews

Customer Reviews

Your Journey

How to use it — practical directions

Simple daily use and safety considerations based on the product formulation.

Serving

Take one capsule twice daily

Use 1 capsule two times per day, 12 hours apart.

Timing and manner

With or between meals

Take each dose with or between meals as part of your regular routine.

Contraindications and interactions

Not for people with bleeding tendencies; consult before combining with certain medications or during pregnancy/lactation

Do not use if you have a history of bleeding tendency or conditions associated with bleeding. Consult a health professional before use if you are taking anticoagulant or blood pressure medications, or if you are pregnant or lactating.

Storage and format

Vegetable capsule; store appropriately

Product is supplied in a vegetable capsule; store in a cool, dry place away from excessive heat and humidity.

Product education

Suggested Use: 1 capsule 2 times per day, 12 hours apart, with or between meals.

NSK–SD™ (Nattokinase) – NSK-SD is a powerful enzyme that has demonstrated in clinical trials to support endogenous fibrinolytic activity, thus, dissolving blood clots. This customer favorite, has a long term success rate. NSK-SD is the original Nattokinase formula and is studied extensively in Japan and in the United States. Because this product promotes blood flow and circulation, NSK-SD should not be used by those with bleeding problems. Those using anti-coagulant treatments should consult their doctor before using. Please contact us directly to speak with one of our licensed health professionals for any concerns or questions.

What Is Nattokinase?

A traditional Japanese vegetable-derived cheese used for over 1,000 years, natto has been prized for both its popular taste and vascular support properties. Nattokinase, a fibrinolytic enyzme isolated from natto, helps to maintain healthy activity of the body’s natural clotting and fibrinolytic processes. This enzyme has demonstrated enhanced oral fibrinolytic potential when compared with other fibrinolytic enzymes from over 200 foods.*

Uses For Nattokinase NSK-SD™

Supports Healthy Fibrinolytic Activity And Clotting Function: Fibrinolysis is a natural physiological process. As the body ages, however, endogenous fibrinolytic activity declines. One study suggested that nattokinase inactivates plasminogen activator inhibitor, maintaining healthy fibrinolytic activity. Nattokinase may also directly degrade fibrin in much the same way as plasmin. Furthermore, researchers from JCR Pharmaceuticals, Oklahoma State University and Miyazaki Medical College examined the effect of nattokinase from natto food consumption in 12 healthy Japanese participants. The results suggested that natto supported healthy clotting function compared to placebo.* Promotes Healthy Circulation And Blood Flow: In another study, nattokinase provided positive support for healthy circulation in animals. In an additional animal study conducted by Biotechnology Research Laboratories and JCR Pharmaceuticals of Kobe, Japan, nattokinase promoted healthy blood flow.* Maintains Blood Vessel Function: In 1995, scientists at the Miyazaki Medical College and Kurashiki University in Japan demonstrated the potential for nattokinase to support blood vessel health in human subjects.*

What Is The Source of Nattokinse NSK-SD?

Natto is produced by a fermentation process when Bacillus natto (also known as Bacillus subtilis natto) is added to boiled soybeans. Nattokinase, a fibrinolytic enzyme, is isolated from natto. NSK-SD™ is a registered trademark of Japan Bio Science Laboratories.

How to Use Nattokinase

Pure Encapsulations recommends 1-2 capsules 2 times per day, 12 hours apart, with or between meals.

Are There Any Potential Side Effects Or Precautions with Nattokinase?

This product is contraindicated for individuals with a history of bleeding tendency or with conditions associated with bleeding. If pregnant or lactating, consult your physician before taking this product.

Are There Any Potential Drug Interactions with Nattokinase?

Due to potential synergistic effects, concurrent use with anticoagulant and blood pressure medications should be closely supervised by a health professional.

Supplement record

Review serving details and ingredients for this product.

Supplement Facts:
Suggested Use: 1 capsule 2 times per day, 12 hours apart, with or between meals.
each vegetable capsule contains:
Ingredients AMT %DV
nattokinase (2000 FU) (soy) 100 mg -
vitamin C (as ascorbyl palmitate) 5 mg -
Other Ingredients: (hypo-allergenic plant fiber added to complete capsule volume requirement)
(-) There is no %DV or the manufacturer has not provided this data.