MethylPro

L-Methylfolate 15 mg + Cofactors

$46.50

SIZE: 30 Capsules

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The Promise

Product Identity & Key Features High‑potency active folate formula with cofactors

L‑5‑Methylfolate 15 mg plus active B‑vitamins and magnesium in a vegetarian capsule; allergen‑free.

Active folate form

Provides L‑5‑Methylfolate (L‑methylfolate) delivering 15 mg folate per serving (from 20.8 mg L‑5‑Methylfolate, calcium salt).

Included cofactors

Contains active B‑6 as pyridoxal‑5′‑phosphate (P‑5‑P), active B‑12 as methylcobalamin, plus magnesium.

Formulation & delivery

Vegetarian cellulose capsule; other ingredient: L‑leucine.

Dietary & allergen info

Reported free of the nine major FALCPA allergens (gluten/wheat, eggs, milk, soy, shellfish, fish, peanuts, tree nuts, sesame).

Why It Works

Why this formulation matters Specific active forms and dosages that support methylation biochemistry*

Measured active nutrients and cofactors supplied in bioactive forms to directly enter methylation pathways.

01

Therapeutic L‑Methylfolate dose

Delivers 15 mg folate as L‑5‑Methylfolate (calcium salt) — the ready‑to‑use folate form.

02

Active B‑6 (P‑5‑P)

Includes pyridoxal‑5′‑phosphate; label lists 'Vitamin B‑6 (as 25 mg Pyridoxal 5' Phosphate)' with 15 mg declared amount (882% DV).

03

Active B‑12 (methylcobalamin)

Provides 1,000 mcg methylcobalamin per serving (4,1667% DV as stated on label).

04

Magnesium cofactor

Contains 125 mg magnesium as magnesium citrate (30% DV) to support enzymatic reactions.*

Reviews

Customer Reviews

Your Journey

How to use & safety Follow professional guidance; see label directions and warnings

Suggested use and precautions as provided on the product label.

Suggested use

Use as directed by a healthcare professional

Follow dosing and timing recommended by your clinician; product label lists 'Suggested Use: Use as directed by a healthcare professional.'

Ingredients & capsule

Capsule format and excipients

Supplied in a vegetarian cellulose capsule; other ingredient: L‑leucine.

Allergen & storage note

Allergen status

Reported free of the nine major FALCPA allergens (wheat/gluten, eggs, milk, soybeans, shellfish, fish, peanuts, tree nuts, sesame).

Warnings & precautions

Pregnancy, lactation, medications

Pregnant or lactating women and individuals taking prescription medications should consult a healthcare professional before taking any supplement.

Product education

L-Methylfolate 15 mg with Cofactors: A High-Potency Formula for Methylation Support*

MethylPro’s L-Methylfolate 15 mg with Cofactors is a therapeutic-strength supplement designed to provide robust support for the body’s methylation cycle. This advanced formula delivers a high-potency 15-mg dose of L-5-Methylfolate, the body’s most active and bioavailable form of folate. It is synergistically enhanced with the essential cofactors needed for its optimal utilization: active B6 (P-5-P), active B12 (methylcobalamin), and magnesium. It is an ideal choice for individuals with MTHFR genetic variations or those needing significant support for mood, cardiovascular health, and detoxification.*

How It Works: Fueling the Methylation Engine

This formula provides the crucial nutrients that act as fuel and spark plugs for the body’s essential methylation processes.

Direct Support with Active Folate
The cornerstone of this product is a 15-mg dose of L-Methylfolate. This ready-to-use form of folate bypasses potential genetic hurdles in the body, providing a direct source for methylation. This process is vital for producing key neurotransmitters like serotonin and dopamine, which is why this formula is excellent for supporting a positive mood and cognitive function.*

Essential Cofactors for Optimal Efficacy
For folate to work effectively, it relies on key cofactors. This formula includes active Vitamin B6 (P-5-P) and active Vitamin B12 (methylcobalamin), which are critical for the enzymes that regulate the methylation cycle and help maintain healthy homocysteine levels. In addition, Magnesium is included as it’s an essential mineral cofactor for hundreds of enzymatic reactions, including those involved in nervous system health.*

  • Provides a high-potency 15mg dose of active L-Methylfolate
  • Enhanced with the essential cofactors B6, B12, and Magnesium
  • Ideal for individuals with MTHFR variants needing robust methylation support*
  • Supports a positive mood and healthy neurotransmitter production*
  • Helps maintain healthy homocysteine levels for cardiovascular wellness*

Supplement record

Review serving details and ingredients for this product.

Supplement Facts:
Suggested Use: Use as directed by a healthcare professional.
Ingredient Amount %DV
Vitamin B-6 (as 25 mg Pyridoxal 5' Phosphate) 15 mg 882%
Folate (15 mg folate from 20.8 mg L-5-Methylfolate, calcium salt) 25 mg DFE 6250%
Vitamin B-12 (as Methylcobalamin) 1000 mcg 41667%
Magnesium (as Magnesium Citrate) 125 mg 30%
Other ingredients: vegetarian cellulose capsule, L-leucine.
*Daily Value (DV) not established.
According to information provided by our suppliers, this product is free of the nine major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, shellfish, fish, peanuts, tree nuts, and sesame.
WARNING Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.