Pure Encapsulations

Glucosamine + Chondroitin with Manganese

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SKU: 2581 Category: Product Brand:

The Promise

Concentrated joint-building blend — glucosamine, chondroitin, manganese ascorbate

A three‑ingredient formula combining glucosamine HCl, chondroitin sulfate and manganese ascorbate in a vegetable capsule.

Key actives and amounts

Each capsule supplies 500 mg glucosamine HCl, 400 mg chondroitin sulfate and 2 mg manganese (as manganese ascorbate).

Ingredient sources and forms

Glucosamine HCl is derived from crab and shrimp; chondroitin sulfate is bovine; manganese is supplied as an ascorbate salt.

Delivery and formulation notes

Delivered in a vegetarian cellulose capsule with ascorbyl palmitate included as an additional antioxidant ingredient.

Available sizes

Available in 120‑capsule and 360‑capsule bottles for short‑term initial dosing or longer maintenance supply.

Why It Works

Why these ingredients matter — roles and complementary actions

Each component targets a different aspect of connective tissue composition or protection.

01

Glucosamine HCl

Glucosamine promotes synthesis of glycosaminoglycans such as chondroitin sulfate, supporting cartilage building blocks.*

02

Chondroitin sulfate

Chondroitin sulfate is a primary structural compound of articular cartilage and helps block activity of degradative enzymes.*

03

Manganese ascorbate

Manganese supports glycosaminoglycan and mucopolysaccharide production and encourages antioxidant activity of superoxide dismutase.*

04

Ascorbate

Ascorbate (vitamin C) is important for proper collagen formation and also serves as an antioxidant in the formula.

Reviews

Customer Reviews

Your Journey

How to use it — serving, timing, allergies, and supply

Simple dosing guidance for starting and maintaining use, plus safety and supply notes.

Initial dosing

Start with three capsules daily

Take 1 capsule three times per day with meals for 2–3 weeks as the initial dose.

Maintenance dosing

Reduce to two capsules daily

After the initial period take 1 capsule twice daily with meals for maintenance.

Allergy and source caution

Contains shellfish and bovine ingredients

Contains glucosamine derived from crab and shrimp and bovine chondroitin; avoid or consult a clinician if you have shellfish or bovine‑source concerns.

Capsule type and supply planning

Vegetarian capsule; plan supply by bottle size

Formulated in a vegetable (cellulose) capsule; choose 120‑ or 360‑capsule packs based on your chosen dosing schedule.

Product education

Suggested Use: Initial dose: 3 capsules per day, in divided doses, with meals. Maintenance dose: 2 capsules per day, in divided doses, with meals.

Glucosamine + Chondroitin with Manganese – This convenient formula combines two of the most important cartilage building blocks, glucosamine and chondroitin, with manganese ascorbate for enhanced connective tissue support. Glucosamine promotes the synthesis of glycosaminoglycans, such as chondroitin sulfate. The primary structural compound of articular cartilage, chondroitin sulfate also helps to block the activity of degradative enzymes.

This convenient formula combines two of the most important cartilage building blocks, glucosamine and chondroitin, with manganese ascorbate for enhanced connective tissue support. Glucosamine promotes the synthesis of glycosaminoglycans, such as chondroitin sulfate. The primary structural compound of articular cartilage, chondroitin sulfate also helps to block the activity of degradative enzymes. Together, glucosamine and chondroitin may provide synergistic support for healthy hyaluronic acid content and synovial fluid. The trace mineral manganese plays a key role in supporting glycosaminoglycan and mucopolysaccharide production and encourages the antioxidant activity of superoxide dismutase. Ascorbate is a vital nutrient for proper collagen formation and also serves as an antioxidant. In a recent study, the combination of glucosamine HCl, chondroitin sulfate and manganese ascorbate demonstrated the ability to promote joint function.*

Pure Encapsulations Glucosamine/Chondroitin with Manganese is a powerful, complementary formula supporting optimal joint mobility and integrity.*

Supplement record

Review serving details and ingredients for this product.

Supplement Facts:
Suggested Use:Initial dose: 1 capsule, 3 times daily, with meals, for 2-3 weeks. Maintenance dose: 1 capsule, 2 times daily, with meals. Individual results may vary.
each vegetable capsule contains:
Ingredients AMT %DV
glucosamine HCl (crab, shrimp) 500 mg. -
chondroitin sulfate (bovine) 400 mg. -
manganese (ascorbate) 2 mg. -
Other Ingredients: -vegetarian capsule (cellulose, water), ascorbyl palmitate
Contains shellfish (crab, shrimp)
(-) There is no %DV or the manufacturer has not provided this data.