Pure Encapsulations

B6 Complex

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SKU: 2419 Category: Product Brand:

The Promise

Complete B‑Complex with extra B6 — Enhanced vitamin B6 and active folate

A vegetarian capsule blend supplying the full range of B vitamins with additional vitamin B6 and active folate.

Broad-spectrum B vitamin blend

Provides B1, B2, B3, B5, B6, B12, biotin and folate in a single formula for daily B support.*

Enhanced vitamin B6

Includes pyridoxine hydrochloride plus a portion of pyridoxal‑5'‑phosphate for both standard and activated B6 forms.

Active folate as Metafolin®

Folate is supplied as L‑5‑MTHF (Metafolin®), the bioactive folate form that bypasses multiple activation steps.

Methylcobalamin B12 form

Vitamin B12 is provided as methylcobalamin at 1000 mcg per capsule.

Why It Works

Why these forms matter — practical formulation details

The formula pairs conventional and activated B‑vitamin forms and includes supporting nutrients and excipients chosen for stability and vegetarian use.*

01

Activated B2 and B6 fractions

Riboflavin includes riboflavin‑5'‑phosphate and a portion of vitamin B6 includes pyridoxal‑5'‑phosphate to supply already‑activated cofactors.

02

L‑5‑MTHF instead of folic acid

Folate is delivered as Metafolin® (L‑5‑MTHF), the naturally occurring, universally metabolized folate metabolite.

03

Combination niacin formats

Niacin is supplied as both niacinamide and inositol hexaniacinate, offering a no‑flush niacin option.

04

Added choline and inositol

The formula includes choline bitartrate (30 mg) and inositol (25 mg) as complementary cytosolic nutrients.

Reviews

Customer Reviews

Your Journey

How to use this capsule — simple daily guidance

Take as directed for daily B support and store like other supplements.

Serving size

One capsule daily

Suggested use is 1 capsule daily with a meal; the brand also recommends 1–2 capsules per day in divided doses if desired.

Dietary fit

Vegetarian capsule

Delivered in a vegetable cellulose capsule suitable for vegetarian diets.

Storage and handling

Standard supplement storage

Keep capsules stored dry and at room temperature like other vitamin supplements.

Pregnancy and medications

Precautions for some users

If pregnant or lactating consult your physician; folate may interact with certain chemotherapeutic agents.

Product education

Suggested Use: 1 capsule daily, with a meal

B6 Complex – Pure Encapsulations offers a B6 Complex with enhanced vitamin B6. This formula incorporates the B-Complex formula with enhanced vitamin B6 for additional benefit. Taking enhanced B6 is especially helpful for adrenal issues, and for women of all ages. Questions on this or any other products, please call us to speak with one of our licensed health professionals, we are happy to assist you personally.

What Is It?

B6 Complex is an exceptional combination of B vitamins, including vitamins B1, B2, B3, B5, B6, B12, biotin, and folic acid (as Metafolin® L-5-MTHF), all of which are provided in their optimal bioavaiable and functional forms. This formula offers the wide ranging support of B-Complex Plus with added vitamin B6 for enhanced support for cardiovascular, nerve and metabolic system health.*

Features Include

  • Vitamin B6 (pyridoxine HCl and pyridoxal 5′ phosphate), supporting amino acid metabolism, nervous system health, and neurotransmitter (i.e. GABA and serotonin) synthesis, which studies have reported may help promote menstrual comfort. Furthermore, pyridoxine supports healthy red blood cells by participating in hemoglobin synthesis and some studies indicate it supports wrist nerve comfort.*
  • Vitamin B1 (thiamine HCl), processing carbohydrates, fat, and protein via its coenzyme form of thiamine pyrophosphate (TPP). Vitamin B1 is required to form adenosine triphosphate (ATP), the key source of energy for the body. Thiamine also promotes neural health.*
  • Vitamin B2 (riboflavin and riboflavin 5′ phosphate), metabolizing nutrients and participating in electron transport to form ATP. Riboflavin is an integral part of fatty acid catabolism or β-oxidation and helps convert folic acid and vitamin B6 to their active states.*
  • Vitamin B3 (niacinamide and inositol hexaniacinate), supporting cardiovascular health by mediating healthy lipid and carbohydrate metabolism.*
  • Vitamin B5 (calcium pantothenate), supporting cardiovascular health. Pantothenic acid is vital in the healthy production, transportation, and breakdown of lipids. Furthermore, this B vitamin promotes the production of the neurotransmitter acetylcholine.*
  • Vitamin B12 (methylcobalamin), supporting healthy nerve cell activity and DNA replication. Vitamin B12 is a vital component of the methionine synthase pathway, which along with folic acid and vitamin B6 supports healthy homocysteine metabolism and S-adenosylmethionine (SAMe) production.*
  • Folic acid, promoting the production of healthy DNA and chromosomes. Adequate folate status is critical for nucleic acid synthesis and neurotransmitter synthesis. At the molecular level, the main function of folate is to donate methyl groups in key biochemical reactions occurring in blood cells, neurons, the vasculature and many other tissues. It is provided in this formula as Metafolin®, the naturally occurring universally metabolized form of folate. Metafolin® is chemically identical to the active folate metabolite, 5-methyltetrahydrofolate (L-5-MTHF). L-5-MTHF is the predominant, naturally occurring form of folate in food. Through bypassing several enzymatic activation steps, it is directly usable by the body and provides all of the benefits of folic acid regardless of functional or genetic variations. In conjunction with vitamins B12 and B6, folic acid helps to support healthy homocysteine metabolism. Additionally, this B vitamin is important for the growth and reproduction of red and white blood cells.*
  • Biotin, acting as a coenzyme for the metabolism of fat, carbohydrates and protein.*Uses For B6 ComplexThese B vitamins play important roles in nearly all of the physiological systems in the body. Some of the key supportive roles include the maintenance of muscle tone in the GI tract, the functioning of the nervous system, and the integrity of skin, hair, and the liver. Furthermore, these compounds are essential for hemoglobin formation, nerve impulse transmissions, mood, hormone synthesis, and energy metabolism. With enhanced B6, this formula especially promotes healthy cardiovascular, nerve and metabolic functions.*

    What Is The Source?

    Pure Encapsulations B6 Complex formula contains: Vitamin B1 (thiamine HCl): synthetic Vitamin B2 (riboflavin): corn dextrose fermentation Niacinamide and Inositol hexaniacinate: synthetic Vitamin B5 (calcium pantothenate): synthetic Vitamin B6 (pyridoxal HCl): synthetic Vitamin B12 (methylcobalamin): corn dextrose fermentation Folic acid (Metafolin®, L-5-MTHF): synthetic Biotin: synthetic Vitamin C (ascorbyl palmitate) is derived from corn dextrose fermentation and palm oil. Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany.

    Recommendations

    Pure Encapsulations recommends 1-2 capsules per day, in divided doses with meals.

    Are There Any Potential Side Effects Or Precautions?

    At this time, there are no known side effects or precautions. If pregnant or lactating, consult your physician before taking this product.

    Are There Any Potential Drug Interactions?

    Folic acid may adversely interact with chemotheraputic drugs. —

Supplement record

Review serving details and ingredients for this product.

Supplement Facts:
Suggested Use: 1 capsule daily, with a meal
Each vegetable capsule contains:
Ingredients AMT %DV
thiamin (as thiamin HCl) (B1) 100 mg -
Riboflavin (as vitamin B2 and 67% riboflavin 5' phosphate (activated B2)) 15 mg -
Niacin (as niacinamide and 9% inositol hexaniacinate (no-flush niacin)) 010 mg -
Vitamin B6 (as pyridoxine HCl and 5% pyridoxal 5' phosphate (activated B6)) 200 mg -
folate (as Metafolin®, L-5-MTHF) 400 mg -
Pantothenic acid (calcium pantothenate) (B5) 100 mg -
Methylcobalamin (B12) 1000 mcg -
biotin 400 mcg -
pantothenic acid (as calcium pantothenate)(B5) 100 mcg -
Choline bitartrate 30 mg -
Inositol 25 mg -
Other Ingredients: vegetarian capsule (cellulose, water), ascorbyl palmitate
(-) There is no %DV or the manufacturer has not provided this data.