Thorne Research

B-Complex #12

$26.00

SIZE: 60 Capsules

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The Promise

Identity & Formulation Active, tissue-ready B vitamins in a yeast-free capsule

B-Complex #12 supplies eight water‑soluble B vitamins plus choline, using bioactive forms where applicable.

Brand & Product

Thorne Research B-Complex #12 — single‑capsule B-vitamin complex.

Active Forms

Provides methylcobalamin (vitamin B12) and L‑5‑MTHF (Quatrefolic®) folate as the active, tissue‑ready forms.

Complete B Profile

Includes thiamin, riboflavin (riboflavin‑5'‑phosphate), niacinamide, pantothenic acid, pyridoxine/pyridoxal‑5'‑phosphate, biotin, plus choline.

Quality & Excipients

Yeast‑free; third‑party tested for label accuracy and contaminants. Capsule: hypromellose (cellulose) with microcrystalline cellulose, leucine, calcium laurate, silicon dioxide.

Why It Works

Why These Ingredients Concrete formulation details and supported nutrient roles

Amounts, specific forms, and supported physiological roles shown on the label.

01

Labelled Potency per Capsule

Thiamin 40 mg; Riboflavin 25 mg (as R5P); Niacinamide 80 mg; Vitamin B6 total 23.4 mg; Biotin 80 mcg; Pantothenic acid 45 mg.

02

Folate and B12 Levels

Folate 400 mcg as L‑5‑MTHF (667 mcg DFE, Quatrefolic®); Vitamin B12 600 mcg as methylcobalamin (25,000% DV).

03

Bioactive Cofactor Forms

Riboflavin supplied as riboflavin‑5'‑phosphate and vitamin B6 supplied partly as pyridoxal‑5'‑phosphate — active cofactor forms.

04

Documented Nutrient Roles

Label notes roles including normal red blood cell formation, methylation, homocysteine metabolism, DNA synthesis, and cellular/tissue repair.

Reviews

Customer Reviews

Your Journey

Use & Safety Labelled directions, storage, and warnings for shopper decisions

Follow labeled serving, observe interactions and allergy/pregnancy guidance.

Serving

Suggested Use

Take 1 capsule one to three times daily or as recommended by your health‑care practitioner.

Format & Storage

Keep Out of Reach

Hypromellose (vegetarian) capsule; store per package instructions and keep out of reach of children.

Allergy & Pregnancy

Allergy / Pregnancy Notice

Contraindicated for anyone with hypersensitivity to any ingredient. If pregnant, consult your health‑care practitioner before use.

Drug Interaction

Methotrexate Interaction Guidance

5‑MTHF supplementation is not recommended concurrent with methotrexate cancer therapy; folate does not appear to interfere with methotrexate used for psoriasis or rheumatoid arthritis per label.

Product education

Thorne B-Complex #12: Comprehensive B-Vitamin Support for Energy and Neurological Health*

Thorne’s B-Complex #12 is a comprehensive B-vitamin complex specifically formulated with extra Vitamin B12 and folate to support robust energy production and healthy neurological function. Unlike many multi-B vitamins, this formula provides the active, tissue-ready forms of water-soluble B vitamins, ensuring superior bioavailability.*

Why Active B Vitamins Matter:

Supplementing with the active forms of B vitamins is crucial for everyone, particularly for individuals who may have difficulty converting non-active B vitamins to their usable forms in the liver due to compromised liver function, poorly functioning enzymes, digestive disorders, or increasing age.

Key Benefits and Inclusions:*

  • Optimal B12 and Folate: Vitamin B12 and folate are essential for normal red blood cell formation, comprehensive tissue and cellular repair, healthy methylation processes, proper homocysteine metabolism, and vital DNA synthesis. Thorne’s B-Complex #12 exclusively supplies the active form of vitamin B12 – methylcobalamin – and the active form of folate – 5-MTHF.
  • Complete B-Vitamin Profile: This formula includes eight essential water-soluble B vitamins: thiamin (vitamin B1), riboflavin/riboflavin 5′-phosphate (vitamin B2), niacinamide (vitamin B3), pantothenic acid (vitamin B5), pyridoxine/pyridoxal 5′-phosphate (vitamin B6), methylcobalamin (vitamin B12), 5-MTHF (folate), and biotin, plus choline.
  • Enhanced Bioavailability: The inclusion of these active cofactors ensures enhanced bioavailability, allowing the body to get the nutrients it needs efficiently.*
  • Synergistic Action: While each B vitamin is chemically distinct, they work synergistically in various biochemical functions throughout the body, supporting everything from cellular energy production to healthy red blood cell formation and optimal neurological function.*
  • Yeast-Free Formula: B-Complex #12 is not derived from yeast.

Addressing B-Vitamin Deficiency:

Most B vitamins, with the exception of vitamin B12, are not stored in the body, necessitating daily dietary intake to maintain optimal health. Vitamin B12 deficiency can manifest with varying degrees of mental changes, including confusion and irritability. Certain prescription medications (for seizures, diabetes, arthritis, and cancer) can also lead to deficiencies in these crucial vitamins. The incidence of vitamin B12 and/or folate deficiency is notably high among the elderly, and pregnant women require an increased amount of folate for proper fetal development. A pre-existing folate deficiency can be intensified during pregnancy.*

Quality Assurance:

This product has undergone rigorous third-party testing and certification to verify that its contents precisely match the label claims and to confirm the absence of unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.

Supplement record

Review serving details and ingredients for this product.

Supplement Facts:
Suggested Use: Take 1 capsule one to three times daily or as recommended by your health-care practitioner.
Serving Size: One Capsule
Ingredient Amount %DV
One Capsule Contains:
Thiamin (as Thiamin HCI) 40 mg 3,333%
Riboflavin (28.6 mg as Riboflavin 5'-Phosphate Sodium) 25 mg 2,200%
Niacin (as Niacinamide) 80 mg 500%
Vitamin B6 (20 mg as Pyridoxine HCI and 3.4 mg as Pyridoxal 5'-Phosphate) 23.4 mg 1,376%
Folate (400 mcg as L-5-Methyltetrahydrofolate† from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 667 mcg DFE 167%
Vitamin B12 (as Methylcobalamin) 600 mcg 25,000%
Biotin 80 mcg 267%
Pantothenic Acid (as Calcium Pantothenate) 45 mg 900%
Choline (as Choline Citrate) 14 mg 3%
Daily Value (DV)
†This product uses Gnosis S.p.A.'s L-5-Methyltetrahydrofolic Acid, Glucosamine Salt (Quatrefolic®). Quatrefolic is a registered trademark of Gnosis S.P.A.
Other Ingredients: Hypromellose (derived from cellulose) capsule, Microcrystalline Cellulose, Leucine, Calcium Laurate, Silicon Dioxide.
Warnings: ALLERGY WARNING: This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PREGNANCY: If pregnant, consult your health-care practitioner before using this product. INTERACTIONS: 5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.
Manufactured by: THORNE RESEARCH, INC., 1-800-228-1966