5-Hydroxytryptophan: A Serotonin Precursor for Mood and Sleep Support*
Thorne’s 5-Hydroxytryptophan (5-HTP) is a high-quality supplement designed to support a healthy mood, manage stress, and promote restful sleep. 5-HTP is a naturally occurring amino acid that serves as the direct building block for the synthesis of serotonin, a crucial neurotransmitter. This formula is enhanced with the active, most usable form of vitamin B6 (P-5-P), an essential cofactor that the body needs to convert 5-HTP into serotonin. It’s a foundational choice for individuals seeking to naturally support their emotional well-being and sleep patterns.*
How It Works: The Science of Serotonin Production
The brain’s level of serotonin is essential for feelings of well-being. This formula works by providing the direct precursors the body needs to optimize its own serotonin production.
Promoting a Positive Mood and Managing Stress
Serotonin is often called the “feel-good” neurotransmitter because of its significant role in regulating mood and emotions. By providing a direct source of 5-HTP, which readily crosses the blood-brain barrier, this supplement helps to maintain healthy serotonin levels. This can promote a positive outlook, help manage feelings of stress, and support emotional resilience.*
Supporting Restful Sleep Cycles
In the brain, serotonin is converted into melatonin, the body’s primary sleep hormone. Therefore, supporting healthy serotonin levels during the day is a key step in promoting the natural production of melatonin at night. By providing the necessary building blocks, 5-HTP helps to regulate the circadian rhythm, making it easier to fall asleep and achieve a more restorative sleep cycle.*
- Promotes a positive mood and emotional well-being*
- Provides the direct precursor for the body’s serotonin production
- Supports restful sleep by aiding in melatonin synthesis*
- Includes active Vitamin B6 (P-5-P) to enhance serotonin conversion
- Sourced from the seeds of the Griffonia simplicifolia plant








