N-acetyl Cysteine (NAC) or glutathione? Which one is better, and most importantly, what do they do for us? There’s been a lot of talk over the past few years on the importance of supplementing with NAC, and then there’s the other side that recommends Glutathione, so let’s dive into the comparison and benefits of each.




Normal dosing recommendations:

  • 600 mg-1800 mg daily


N-acetyl Cysteine is a derivative of the amino acid L-cysteine, which is sulfur based (queue the egg smell). Sulfur is essential for several biological processes, such as protein construction (amino acid building block) and enzyme functions. It is important to note here that sulfur based amino acids are not related to sulfa-based pharmaceuticals, they are completely different.


Lung Support

NAC is often used to help support healthy lung functioning, as it has been shown to decrease the viscosity of mucus, making it easier to expel. It makes this supplement ideal for those with COPD, or chronic lung issues, or just someone looking for additional immune and lung support.


Production of Glutathione

NAC primarily is supplemented to promote the production of glutathione, as it is a necessary component along with glycine and glutamic acid. Glutathione is one of the most vital antioxidants our body produces and supplementing with NAC ensures the body has ample amounts.





Normal dosing recommendations:

  • Reduced Glutathione: 100 mg-200 mg daily

  • Liposomal Glutathione softgel: 250 mg- 500 mg daily

  • Liposomal Glutathione Liquid: 100mg-200 mg daily


Supplementing with active glutathione has been tricky in the past, as it easily becomes broken down before entering the blood stream. With new innovations and research, there are now 3 options for supplemental glutathione that are effective when taken orally; sublingual (liquid), liposomal and reduced.


Critical Antioxidant

Why is glutathione absorption important? This critical antioxidant is found in virtually every cell in the human body and plays a key role in how we process protein, supports enzyme functions and research strongly suggests it has been associated with healthy mental and physical health. High concentrations are found in the liver, where it acts as a powerful antioxidant that supports the detoxification processes and protects the liver from oxidative stress.



Supplement with N-Acetyl Cysteine (NAC)

Personally, I take NAC daily, 1200 mg in divided doses to help support glutathione production and help my lungs keep healthy.

As you can see, glutathione is crucial for overall health. As we age, our body produces less and our ability to create glutathione can be greatly reduced with health complications or genetic issues. Whether you choose to supplement with NAC or glutathione, both are an excellent way to boost this vital antioxidant and support our health.


If I can help with any questions or you’d just like to discuss this topic further, you can email me directly at [email protected]



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N-Acetyl Cysteine (NAC)


Tracy comes to us with extensive knowledge from the holistic health field. She graduated from Natural Success School of Holistics, with her Holistic Health Practitioner certificate. Tracy also holds a certificate in Nutrition and Bachelors in Holistic Nutrition from Clayton College School of Natural Health.

Previously, Tracy was co-owner of an environmentally friendly massage center for several years, located in Encinitas, California. Her holistic massage center focused not only on holistic massage, but also client education on the importance of recycling and reducing waste, choosing healthy products, and proper nutrition.