TMG (trimethylglycine)

by Allergy Research Group

TMG (Trimethylglycine) by Allergy Research Group for Heart Health and Liver Support

TMG (trimethylglycine) by Allergy Research Group is a dietary supplement designed to support healthy homocysteine metabolism and maintain healthy fat metabolism and cellular protection in the liver. This compound, also known as anhydrous betaine, acts as a methyl donor that is crucial for a variety of physiological reactions in the body. TMG works synergistically with other methyl donors such as choline, folic acid, vitamin B12, and s-adenosylmethionine (SAMe), and it serves as a precursor for carnitine synthesis. Additionally, TMG contributes to liver and kidney cellular health while promoting osmotic balance and protecting cellular structures under stress.

✅ Key Benefits

• Supports healthy homocysteine metabolism
• Maintains healthy fat metabolism in the liver
• Acts as a methyl donor for various physiological reactions
• Promotes cellular protection in the liver and kidneys
• Helps improve cellular resilience to osmotic stress

✅ How It Works / Key Ingredients

TMG functions primarily as a methyl donor, which is essential for the conversion of homocysteine to methionine, thereby supporting healthy homocysteine levels. It is particularly beneficial when dietary intake of vitamin B12, folic acid, and vitamin B6 is insufficient. TMG is recognized as a lipotropic factor, which helps maintain healthy fat metabolism in the liver. It also provides methyl groups to convert homocysteine to methionine via the enzyme betaine homocysteine methyltransferase (BHMT), especially active in the liver and kidneys.

✅ Evidence & Research

Research has indicated that a betaine-rich diet or betaine supplementation can support healthy homocysteine metabolism in both men and women. This nutrient is also known to generate s-adenosylmethionine, a vital cofactor for healthy liver function. TMG is effective at lower doses, making it beneficial for individuals with genetic polymorphisms affecting folate metabolism.

✅ Formula & Quality Notes

• Suggested use: 1 capsule one to three times daily before meals, or as directed by a healthcare practitioner
• This form of betaine should not be confused with betaine HCl, which is used for digestive support
• Storage: Keep in a cool, dry place, tightly capped