Pure Encapsulations

Methylcobalamin

Price range: $20.50 through $49.50

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The Promise

Methylcobalamin B12 — Activated, directly usable B12

An activated, highly bioavailable form of vitamin B12 supplied as methylcobalamin.*

Principal active ingredient

Each vegetable capsule delivers 1,000 mcg of methylcobalamin (vitamin B12).

Formulation details

Delivered in hypoallergenic vegetable capsules with plant fiber to complete capsule volume.

No artificial additives

Contains no added artificial sugars or colors and its natural red color is inherent to the ingredient.

Multiple formats and sizes

Offered in capsule counts of 60 and 180, and available in liquid forms for alternate dosing needs.

Why It Works

Why methylcobalamin matters — Specific biochemical roles and sourcing

Methylcobalamin is the principal circulating form of cobalamin and is used in key metabolic pathways.

01

Activated and bioavailable*

Methylcobalamin is an activated form of vitamin B12 that is directly usable by the body.

02

Supports nervous system biochemistry*

This form promotes protein synthesis important for maintaining healthy nerve cells and myelin.*

03

Plays a role in one-carbon metabolism

Works with folate as a cofactor in the methionine synthase pathway affecting homocysteine and SAMe production.

04

Fermentation-derived source

Produced via corn dextrose fermentation, supplying the ingredient without added dyes.

Reviews

Customer Reviews

Your Journey

How to take methylcobalamin — Practical serving and use

Follow suggested dosing and storage considerations to fit this supplement into your routine.

Serving size

Daily dose range

Take 1–3 capsules per day in divided doses.

Timing and administration

Take with meals

Consume the capsules with meals and split doses across the day as needed.

Choose format and supply

Select capsules or liquid

Choose capsules (60 or 180 count) for standard use or the liquid option for higher or alternate dosing.

Pregnancy, lactation, and consultation

Ask a healthcare professional if needed

If pregnant or lactating, consult your physician before use.

Product education

Suggested Use: 1-3 capsules per day, in divided doses, with meals.

Methylcobalamin – Poor memory? Low energy? B12 if often recommended by health professionals for people who complain of lowered energy, and poor mental functioning. Pure Encapsulations uses the activated and more absorbable form of B12, methylcobalamin. Also available in liquid form and for those with extreme deficiencies, Liquid b12 5000 is offered through the Pure Encapsulations line of professional products.

What Is It?

Methylcobalamin is an activated, highly bioavailable form of vitamin B12, which acts as the principal circulating form of cobalamin in the body. It is available in liquid and capsule form.*

Uses For Methylcobalamin

Nervous System Health: In recent studies, methylcobalamin has demonstrated an enhanced ability to support neurological function. This form of vitamin B12 promotes protein synthesis for maintaining healthy nerve cells and myelin. Methylcobalamin may also help to moderate levels of glutamate in the brain, encouraging healthy brain cell activity, as well as memory, mood, and cognitive function. In general, vitamin B12 works with folate to promote DNA and red blood cell health. Additionally, vitamin B12 is an important cofactor for energy metabolism and a vital component of the methionine synthase pathway, which supports healthy homocysteine metabolism and S-adenosylmethionine (SAMe) production.*

What Is The Source?

Pure Encapsulations methylcobalamin is produced from corn dextrose fermentation. It has a naturally occurring red color that does not result from the use of artificial dyes or colors. Neither the capsule or liquid products contain added artificial sugars or added color.

Are There Any Potential Side Effects Or Precautions?

At this time, there are no known side effects or precautions. If pregnant or lactating, consult your physician before taking this product.

Are There Any Potential Drug Interactions?

At this time, there are no known adverse reactions when taken in conjunction with medications.

Supplement record

Review serving details and ingredients for this product.

Supplement Facts:
Suggested Use: 1-3 capsules per day, in divided doses, with meals.
each vegetable capsule contains:
Ingredients AMT %DV
methylcobalamin (vitamin B12) 1,000 mcg. -
Other Ingredients: (hypo-allergenic plant fiber added to complete capsule volume requirement)
(-) There is no %DV or the manufacturer has not provided this data.